Active Native Sambucus Nigra Lectin Protein

• Cat.No.: Lectin-1745S
• Product Overview: This product is the Sambucus Nigra Lectin and and has sugar specificity against Sialic Acid.

Specification

• Species: Sambucus nigra
• Source: Sambucus nigra
• Tag: Non
• Description: Sambucus nigra lectin, isolated from elderberry bark, binds preferentially to sialic acid attached to terminal galactose in α-2,6 and to a lesser degree, α-2,3 linkage. Binding is also inhibited to some extent by lactose or galactose. This lectin does not appear to bind sialic acid linked to N-acetylgalactosamine. SNA has been reported to inhibit cell-free protein synthesis.
• Bio-activity: Elution: 500 mM lactose in buffered saline followed by 500 mM lactose in acetic acid. Binding inhibitors: Fetuin, human transferin, bovine submaxillary mucin,
  porcine thyroglobulin, 6’ sialylactose, 500 mM lactose.
• Molecular Mass: 140 kDa
• Applications: Glycobiology
• Storage: Refrigerate in the dark.
• Reconstitution: Although many buffers can be employed for reconstituting and diluting this lectin, 10 mM HEPES buffered saline, pH 7.5 - 8.5, 0.1 mM Ca2+ is recommended. For preserving solutions stored at 4 centigrade, 0.08% sodium azide can be used.

Gene Information

• Synonyms: Lectin; SNA; EBL
• UniProt ID: O04366