Native Toxoplasma gondii IgM antigen, RH strain

• Cat.No.: IgM-04T
• Product Overview: A highly purified source of Toxoplasma gondii membrane antigens, optimised for IgM detection.

Specification

• Species: T. Gondii, Strain RH
• Source: Vero
• Description: Toxoplasma gondii (T. gondii) is an obligate intracellular parasitic protozoan of the phylum Apicomplexa. It is the causative agent of the disease Toxoplasmosis, a common parasitic zoonoses which is widespread throughout most of the world. The domestic cat and other members of the family Felidae are the only definitive hosts for T.gondii. However, T.gondii is also capable of infecting a wide range of birds and mammals, including humans, which act as intermediate hosts. In domestic cats, sexual replication of T. gondii occurs with the release of oocysts into the environment, in cat faeces. In humans, T. gondii is primarily acquired by ingesting undercooked meat contaminated with bradyzoites (tissue cysts), drinking water contaminated by oocysts, or via accidental ingestion of cat faeces containing oocysts. In pregnant women, infected with T. gondii, vertical transmission of the parasite can occur causing congenital defects, stillbirths or miscarriage. In rare cases, infection via blood transfusion and organ transplant can also occur (CDC).
• Form: Liquid
• Applications: Highly purified and optimised for IgM detection in immunodiagnostic assays.
• Stability: Stability: 1 month at +4 centigrade
  Freezing: Can be frozen
• Storage: Short Term Storage: +4 centigrade
  Long Term Storage: -80 centigrade
• Concentration: 0.57 mg/mL
• Storage Buffer: Presented as liquid in 2% OGP in PBS pH 7.4
• References: 1. Centers for Disease Control and Prevention: Parasites – Toxoplasmosis (Toxoplasma infection)
  2. Black MW, Boothroyd JC. 2000. Lytic cycle of Toxoplasma gondii. Microbiol Mol Biol Rev. Sep;64(3):607-23.

Gene Information

• Official Symbol: IgM
• Synonyms: IgM