Recombinant 2019-nCoV N protein
Cat.No. : | N-127V |
Product Overview : | Recombinant 2019-nCoV N protein was expressed in E. coli and purified by Ni column. |
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Description : | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Source : | E. coli |
Species : | 2019-nCov |
Form : | Liquid. PBS, pH 8.0. |
Molecular Mass : | 47.08 kDa |
Storage : | For short term storage, store at 4 centigrade. For long term storage, store at -20~-70 centigrade, avoiding freeze/thaw cycles. |
Concentration : | 1.0 mg/ml |
Publication : |
Biomaterials and Oxygen Join Forces to Shape the Immune Response and Boost COVID-19 Vaccines (2021)
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Gene Name : | N |
Official Symbol : | N |
Synonyms : | GU280_gp10 |
Gene ID : | 43740575 |
Protein Refseq : | YP_009724397.2 |
Products Types
◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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