Recombinant Active Human RSPO1 Protein, His-tagged(C-ter)
| Cat.No. : | RSPO1-278H |
| Product Overview : | Recombinant Active Human RSPO1 Protein with His tag (C-ter) was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
- Download
| Species : | Human |
| Source : | HEK293 |
| Tag : | His |
| Protein Length : | Arg31-Ala263 |
| Description : | This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| Form : | Powder |
| Bio-activity : | Measured by its ability to enhance Cyclin D1 expression in HCT116 human colon adenocarcinoma cells. 0.1-10 ng/mL of Recombinant Human RSPO1 can effectively enhance Cyclin D1 expression. |
| Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
| Purity : | > 92% (by SDS-PAGE) |
| Applications : | FuncSt, SDS-PAGE |
| Notes : | For laboratory research only, not for drug, diagnostic or other use. |
| Storage : | Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Storage Buffer : | PBS (pH 7.4) |
| Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water. |
| Gene Name | RSPO1 R-spondin 1 [ Homo sapiens ] |
| Official Symbol | RSPO1 |
| Synonyms | RSPO1; R-spondin 1; R spondin homolog (Xenopus laevis); R-spondin-1; FLJ40906; RSPONDIN; R-spondin homolog; roof plate-specific spondin-1; RSPO; CRISTIN3; RP11-566C13.1; |
| Gene ID | 284654 |
| mRNA Refseq | NM_001038633 |
| Protein Refseq | NP_001033722 |
| MIM | 609595 |
| UniProt ID | Q2MKA7 |
Not For Human Consumption!
Inquiry
- Reviews (0)
- Q&As (0)
Ask a Question for All RSPO1 Products
Required fields are marked with *
My Review for All RSPO1 Products
Required fields are marked with *
Recently Viewed
