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Recombinant Chicken ARG2

Cat.No. : ARG2-4463C
Product Overview : Recombinant Chicken ARG2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Chicken
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : ARG2 arginase 2 [ Gallus gallus (chicken) ]
Official Symbol : ARG2
Gene ID : 423272
Protein Refseq : NP_001186633

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (15)

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Are there any natural compounds or dietary factors that can modulate Arg2 activity? 01/16/2023

The modulation of Arg2 activity by natural compounds or dietary factors is an area of ongoing research. Some studies suggest that certain polyphenols, such as quercetin and epigallocatechin gallate (EGCG), may influence Arg2 activity. Additionally, dietary factors like high-protein diets and specific amino acids may affect Arg2 expression and function. However, further investigation is needed to fully understand these modulatory effects.

Can Arg2 be targeted for therapeutic interventions? 08/08/2022

Targeting Arg2 for therapeutic interventions is an area of active research. In cancer, for example, inhibiting Arg2 activity may help limit tumor growth and enhance anti-tumor immune responses. However, more studies are needed to fully understand the implications and potential therapeutic benefits of targeting Arg2 in different diseases.

Are there any diseases associated with Arg2 dysregulation? 08/10/2021

Dysregulation of Arg2 has been implicated in various diseases. Increased Arg2 expression/activity has been observed in certain types of cancer, such as hepatocellular carcinoma, and may contribute to tumor growth and immune evasion. Additionally, alterations in Arg2 expression have been associated with conditions like cardiovascular diseases, kidney disorders, and neurodegenerative diseases.

Is there a link between Arg2 and neurodegenerative diseases? 12/30/2020

There is emerging evidence suggesting a potential link between Arg2 and neurodegenerative diseases. Aberrant arginine metabolism and dysregulation of arginase activity, including Arg2, have been observed in neurodegenerative disorders like Alzheimer's disease and Huntington's disease. Altered arginine metabolism can affect nitric oxide production, which plays a role in neuronal signaling and neuroinflammation. While further research is needed, targeting Arg2 or modulating arginine metabolism could potentially have therapeutic implications for these diseases.

What are the physiological roles of Arg2 in the body? 10/14/2019

Arg2 serves several physiological roles in the body. It participates in the urea cycle, a pathway involved in nitrogen disposal and maintaining ammonia homeostasis. By converting arginine to urea and ornithine, Arg2 contributes to the removal of toxic ammonia from the body. Additionally, Arg2 is involved in the regulation of nitric oxide (NO) production, which affects vascular tone and immune responses.

Can Arg2 be regulated by dietary factors? 09/03/2019

Yes, dietary factors can influence the expression and activity of Arg2. For example, high protein diets can increase Arg2 expression and activity, as they provide more arginine as a substrate for the enzyme. Additionally, certain amino acids and metabolites, such as citrulline and ornithine, can modulate Arg2 activity. However, the exact mechanisms by which dietary factors regulate Arg2 are still being investigated.

Can Arg2 activity be measured in clinical settings? 10/03/2018

Yes, Arg2 activity can be assessed in clinical settings. Multiple methods have been developed to measure Arg2 enzyme activity, often involving the analysis of enzyme kinetics and substrate/product concentrations. However, it is important to note that the measurement of Arg2 activity is not commonly used as a routine clinical test and is primarily performed in research or specialized laboratories.

Can Arg2 play a role in cancer? 12/13/2017

Yes, Arg2 has been implicated in cancer development and progression. Elevated levels of Arg2 have been observed in various types of cancers, including breast, prostate, colorectal, and brain cancers. Arg2 expression can promote cancer cell proliferation, invasion, and metastasis. It can also contribute to immune evasion by inhibiting T-cell function and suppressing anti-tumor immune responses. Targeting Arg2 in cancer therapy has shown promising results as a potential strategy to inhibit tumor growth and enhance the effectiveness of immunotherapies.

Does Arg2 have any potential therapeutic applications beyond disease treatment? 05/19/2017

Besides its potential role as a therapeutic target in various diseases, Arg2 may have other therapeutic applications. For instance, it has been explored in the field of organ transplantation, where targeting Arg2 can potentially modulate immune responses and reduce rejection rates. Furthermore, understanding Arg2's involvement in metabolism and cellular functions could lead to the development of novel strategies for metabolic diseases or improving protein utilization in nutritional interventions.

Are there any known genetic variants or mutations in the Arg2 gene? 02/28/2017

While specific genetic variants or mutations in the Arg2 gene have not been extensively studied, some studies have identified single nucleotide polymorphisms (SNPs) in the regulatory regions of the Arg2 gene that may be associated with certain diseases or phenotypic traits. However, more comprehensive genetic studies are needed to fully understand the genetic variability of Arg2 and its potential implications.

Can Arg2 be involved in reproductive processes? 02/09/2017

Yes, Arg2 has been found to be involved in various reproductive processes. For example, it plays a role in sperm function and male fertility by regulating the availability of arginine for the production of nitric oxide, which is important for sperm motility. Moreover, Arg2 expression and activity can be influenced by hormonal changes during pregnancy. Overall, the precise mechanisms and significance of Arg2 in reproductive processes are still being explored.

Are there any known inhibitors or activators of Arg2? 01/27/2017

Several chemical compounds have been identified as inhibitors of Arg2. For example, nor-NOHA (N(W)-hydroxy-nor-l-arginine) is a commonly used competitive inhibitor of Arg2 that selectively inhibits its enzymatic activity. Other compounds such as S-(2-boronoethyl)-L-cysteine (BEC) and Nω-hydroxy-nor-L-arginine (nor-NOHA) have also shown inhibitory effects on Arg2 activity. As for activators, there is currently limited research on specific molecules that can directly activate Arg2.

What happens when Arg2 is deficient or absent? 01/09/2017

Complete Arg2 deficiency is extremely rare, and individuals with this genetic disorder typically exhibit hyperargininemia, a condition characterized by elevated levels of arginine in the blood. This can lead to symptoms such as intellectual disability, developmental delays, and seizures. However, the specific consequences of Arg2 deficiency may vary depending on factors like compensatory mechanisms and the individual's genetic makeup.

Is there any association between Arg2 and inflammation? 05/18/2016

Yes, Arg2 has been linked to inflammation. Its expression can be induced by various pro-inflammatory stimuli, suggesting a potential role in immune responses. Moreover, Arg2-mediated metabolism of arginine can impact the production of molecules like polyamines, proline, and ornithine that play roles in wound healing and tissue repair processes associated with inflammation.

Are there any known pharmacological inhibitors of Arg2? 03/28/2016

Yes, there are pharmacological inhibitors of Arg2 that have been identified. Some examples include Nω-hydroxy-nor-L-arginine (nor-NOHA) and S-(2-boronoethyl)-L-cysteine (BEC). These inhibitors have shown promise in preclinical studies and are being investigated for their potential as therapeutic agents.

Customer Reviews (8)

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Reviews
04/21/2022

    This flexibility enables researchers like myself to tailor ARHGAP17A protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.

    03/14/2022

      From recombinant protein production to modification or labeling services, the company is committed to assisting researchers in obtaining the Arg2 protein in the format and specifications required for their particular studies.

      08/25/2021

        Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.

        02/09/2019

          Its purity, integrity, and consistency ensure reliable and reproducible results, which are essential for meaningful scientific discoveries.

          02/04/2019

            Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.

            09/21/2017

              the Arg2 protein's exceptional qualities, combined with the manufacturer's comprehensive technical support, make it an ideal choice for researchers seeking reliable experimental materials and reliable assistance in their scientific endeavors.

              06/03/2017

                Their in-depth understanding of the protein's characteristics, applications, and potential limitations allows for valuable insights and recommendations, ensuring the success of my experiments.

                12/11/2016

                  Whether it's troubleshooting, protocol optimization, or general inquiries, their knowledgeable and responsive team is readily available to assist and solve any problems that may arise during the experimental process.

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