Recombinant COVID-19 N protein (nucleocapsid phosphoprotein), Flag-tagged

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Recombinant COVID-19 N protein (nucleocapsid phosphoprotein), Flag-tagged

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Cat.No. : N-128V
Product Overview : Recombinant COVID-19 N protein (nucleocapsid phosphoprotein) was fused to Flag(DYKDDDDK) tag and expressed in Human cells.
Description : Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Source : Human cells
Species : COVID-19
Tag : Flag
Form : Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives.
Molecular Mass : 49.4 kDa
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining.
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Gene Name : N
Official Symbol : N
Synonyms : GU280_gp10
Gene ID : 43740575
Protein Refseq : YP_009724397.2

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