Recombinant COVID-19 S1 (A570D) protein, His-tagged
|Product Overview :||Recombinant COVID-19 S1 (A570D) protein(YP_009724390.1)(Val 16 - Arg 685), fused to His tag at the C-terminus, was expressed in HEK293.|
- Gene Information
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|Description :||It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.|
|Form :||Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.|
|Molecular Mass :||The protein has a calculated MW of 76.9 kDa. The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Protein length :||Val 16 - Arg 685|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||>90% as determined by SDS-PAGE.|
|Storage :||For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.|
|Gene Name :||S surface glycoprotein [ Severe acute respiratory syndrome coronavirus 2 ]|
|Official Symbol :||S|
|Synonyms :||Spike; S1 protein; Spike glycoprotein Subunit1; S glycoprotein Subunit1; Spike protein S1; COVID-19|
|Gene ID :||43740568|
|Protein Refseq :||YP_009724390.1|
|UniProt ID :||P0DTC2|
|Spike-001HCL||Recombinant HCoV-EMC/2012 Spike cell lysate||+Inquiry|
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