| Description : |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
| Source : |
HEK293 |
| Species : |
Cynomolgus |
| Tag : |
C-hFc-Avi |
| Protein length : |
Asp22-Thr48 |
| Conjugation/Label : |
Biotin |
| Form : |
Lyophilised |
| Endotoxin : |
Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). |
| Notes : |
FOR RESEARCH USE ONLY (RUO). |
| Storage : |
The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade. |
| Storage Buffer : |
Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM |
