- Bovine(1)
- Cynomolgus(2)
- Feline(1)
- Human(1)
- Rat(1)
Recombinant Cynomolgus FCGRT & B2M protein, His-Avi-tagged, Biotinylated
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Cat.No. : | FCGRT & B2M-103CB |
Product Overview : | Biotinylated Recombinant Cynomolgus FcRn Protein is expressed from mammalian with a His tag and Avi Tag at the C-terminal.. It contains Met1-Ser297(FCGRT) & Met1-Met119(B2M). |
Description : | The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer. |
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 48-50KD based on Bis-Tris PAGE result. |
Protein length : | It contains Met1-Ser297(FCGRT) & Met1-Met119(B2M) . |
Endotoxin : | Less than 0.05EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
Tris-Bis PAGE : |
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HPLC data : |
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Gene Name : | FCGRT Fc fragment of IgG receptor and transporter [ Macaca fascicularis (crab-eating macaque) ] |
Official Symbol : | FCGRT; B2M |
Synonyms : | FcRn alpha chain; alpha-chain; Fc fragment of IgG, receptor, transporter, alpha; FCGRT; FCRN; FCRNimmunoglobulin receptor, intestinal, heavy chain; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig |
Gene ID : | 102128913 |
mRNA Refseq : | NM_001284551.1 |
Protein Refseq : | NP_001271480.1 |
UniProt ID : | Q8SPV9 |
◆ Recombinant Protein
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FCGRT & B2M-379F | Recombinant Feline FCGRT & B2M Heterodimer Protein, His & Avi-tagged, Biotinylated | +Inquiry |
FCGRT & B2M-1535RB | Recombinant Rat FCGRT/B2M protein, His-tagged, Biotinylated | +Inquiry |
FCGRT & B2M-103C | Recombinant Cynomolgus FCGRT & B2M protein, His-Avi-tagged | +Inquiry |
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