Recombinant Cynomolgus FCGRT & B2M protein, His-Avi-tagged, Biotinylated
Cat.No. : | FCGRT & B2M-103CB |
Product Overview : | Biotinylated Recombinant Cynomolgus FcRn Protein is expressed from mammalian with a His tag and Avi Tag at the C-terminal.. It contains Met1-Ser297(FCGRT) & Met1-Met119(B2M). |
- Specification
- Gene Information
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Description : | The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer. |
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 48-50KD based on Bis-Tris PAGE result. |
Protein length : | It contains Met1-Ser297(FCGRT) & Met1-Met119(B2M) . |
Endotoxin : | Less than 0.05EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | FCGRT Fc fragment of IgG receptor and transporter [ Macaca fascicularis (crab-eating macaque) ] |
Official Symbol : | FCGRT; B2M |
Synonyms : | FcRn alpha chain; alpha-chain; Fc fragment of IgG, receptor, transporter, alpha; FCGRT; FCRN; FCRNimmunoglobulin receptor, intestinal, heavy chain; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig |
Gene ID : | 102128913 |
mRNA Refseq : | NM_001284551.1 |
Protein Refseq : | NP_001271480.1 |
UniProt ID : | Q8SPV9 |
Products Types
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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