Recombinant Cynomolgus monkey DCPS Protein, His-tagged

• Cat.No.: DCPS-01C
• Product Overview: Recombinant Cynomolgus monkey DCPS protein with a His-tag was expressed in E. coli

Specification

• Description: This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
• Source: E. coli
• Species: Cynomolgus monkey
• Tag: His
• Molecular Mass: The protein has a calculated MW of 40.7 kDa.
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMADAA PQLGKRKRELDVEEAHAASTEEKEA GVGNGTCAPVRLPFSGFRVQKVLRE SARDKIIFLHGKVNESSGDGDGEDA VVILEKTPFQVEQVAQLLTGSPELQ LQFSNDIYSTYHLFPPRQLSDVKTT VVYPATEKHLQKYLRQDLRLIRETG DDYRNITLPHLESQSLSIQWVYNIL DKKAEADRIVFENPDPSDGFVLIPD LKWNQQQLDDLYLIAICHRRGIRSL RDLTPEHLPLLRNILHQGQEAILQR YQMKGDRLRVYLHYLPSYYHLHVHF TALGFEAPGSGVERAHLLAEVIENL ECDPRHYQQRTLTFALRADDPLAQA LAGGSAKLN
• Purity: >90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.145 mg/mL
• Storage Buffer: 50mM Tris, 300mM NaCl, pH 8.0

Gene Information

• Gene Name: DCPS decapping enzyme, scavenger [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: DCPS
• Synonyms: DCPS; decapping enzyme, scavenger; LOW QUALITY PROTEIN: m7GpppX diphosphatase
• Gene ID: 717749
• mRNA Refseq: XM_015116079
• Protein Refseq: XP_014971565