Recombinant Cynomolgus monkey DCPS Protein, His-tagged

Species :	Cynomolgus
Source :	E.coli
Tag :	His
Description :	This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
Molecular Mass :	The protein has a calculated MW of 40.7 kDa.
AA Sequence :	MGSSHHHHHHSSGLVPRGSHMADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRVQKVLRESARDKIIFLHGKVNESSGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLSDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYQMKGDRLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLAQALAGGSAKLN
Purity :	>90% by SDS-PAGE
Storage :	Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Concentration :	0.145 mg/mL
Storage Buffer :	50mM Tris, 300mM NaCl, pH 8.0

Gene Name	DCPS decapping enzyme, scavenger [ Macaca mulatta (Rhesus monkey) ]
Official Symbol	DCPS
Synonyms	DCPS; decapping enzyme, scavenger; LOW QUALITY PROTEIN: m7GpppX diphosphatase
Gene ID	717749
mRNA Refseq	XM_015116079
Protein Refseq	XP_014971565