Recombinant Escherichia Coli Protein Disaggregation Chaperone

• Cat.No.: ClpB-619E
• Product Overview: Recombinant Escherichia Coli ClpB is produced in E. coli.

Specification

• Species: E.coli
• Source: E.coli
• Tag: Non
• Description: Caseinolytic peptidase B protein homolog is an enzyme that in humans is encoded by the CLPB gene, which encodes an ATP-dependent protease and chaperone; it is a chaperone involved in disaggregating proteins and also has a role in de novo protein synthesis under mild stress conditions.
• Purity: ≥95%.
• Formulation: Liquid. In 20mM TRIS-HCl, pH 7.8, containing 80mM sodium chloride, 5mM magnesium dichloride, 0.5mM EDTA and 10% (v/v) glycerol.
• Storage: -80°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: clpB protein disaggregation chaperone [ Escherichia coli str. K-12 substr. MG1655 ]
• Synonyms: clpB; protein disaggregation chaperone; ECK2590; htpM; heat shock protein
• Gene ID: 947077
• Protein Refseq: NP_417083

Citation

Congenital heart block and immune mediated sensorineural hearing loss: possible cross reactivity of immune response.

Journal: Lupus    PubMed ID: 27913750    Data: 2018/4/3

Authors: C Bason, I Pagnini, R Cimaz

Article Snippet:All patients’ sera were tested for the presence of antibodies directed against the inner ear antigens (anti-Cogan, anti-DEP1/CD148 and anticonnexin 26 peptides), against the reovirus peptide, and against the 60 kD SSA/Ro peptide.All patients’ sera were tested for the presence of antibodies directed against the inner ear antigens (anti-Cogan, anti-DEP1/CD148 and anticonnexin 26 peptides), against the reovirus peptide, and against the 60 kD SSA/Ro peptide.. The recombinant human TROVE Domain Family, member 2 (rHuRo-60) (TROVE2) in Escherichia Coli, purchased from Creative BioMart (NY, USA) , was also used in an ELISA test.. The five synthetic peptides, namely the Cogan peptide (SGRDTS IQILWI); the DEP1/CD148 peptide (NISATS LTLIWK); the reovirus peptide (GGSVTSLE NLWD); the connexin 26 peptide (NKHSTSIGK IWL) and the 60 kD SSA/Ro peptide (GGTDC SLPMIWA) were purchased from TIBMolbiol (Italy).The five synthetic peptides, namely the Cogan peptide (SGRDTS IQILWI); the DEP1/CD148 peptide (NISATS LTLIWK); the reovirus peptide (GGSVTSLE NLWD); the connexin 26 peptide (NKHSTSIGK IWL) and the 60 kD SSA/Ro peptide (GGTDC SLPMIWA) were purchased from TIBMolbiol (Italy).