Recombinant Full Length Feline Herpesvirus 1 Envelope Glycoprotein H(Gh) Protein, His-Tagged

• Cat.No.: RFL14428FF
• Product Overview: Recombinant Full Length Feline herpesvirus 1 Envelope glycoprotein H(gH) Protein (P13160) (22-821aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Feline herpesvirus 1 (FeHV-1) (Feline viral rhinotracheitis virus)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length of Mature Protein (22-821)
• AA Sequence: LPMMDRPDEGGLARRTVGEVEGEFS YRDDVDVADVRNLFIMLPKNGSDIF LFIFDRRSQR QRGTMFLFPKAGFVQPTPAKVRDEA AAAPFGFISPVYPLSSLLFNPYNGR YLTTRHLIAF EVTPESSLHDWYFARSPTTATQTQP LGHITNPPRRSPKDKPTTSGHTDLI IRYCALELDF FQDTRRQRDGIYLPNYEAVWPLAMN FLEGMWIWSNRTLVNVTIGVGFMGF SLTSISYPPL EIIVTPHYTNARMITRFKSSLVLDP PGPSEGPLYKVYVLGYGNNRINGSF YKTMRTIASY PRTKPRLSLPPFHGTYGTALFLSHA TPQDMDGTTAYISKISTRLATALFS LSEVRRLSGY VAIDELIDLDFNTRLLANTLLADGM QNFQDPINITYYYNSDVGRTHLRDA LDTIDHQHVS HGSLITRARYLQLIYTYTSMEKQSQ LSLKLSGDIVKDLYLETLYSDVVRW NTTAKQALFL SSMLIYIAGNIQSSVEQEAINAGRM LFLQCTSMCTTEHASTVRWNPQQIL YDLTKSSTRF NIFDGFSPCMASNRYDIISPYGILD LFSAFPISSYRSIEKPAVDSNTHNI IFNLRNLYTF IPELFSCPGVSSNHQRPIAVLPIGI NCTYLITRRDPRRGTLYIVDGIDVS NPIIISYLRS GECGIERGIILPGNLNNPENTDQCL YCGCVFMRYKSSGEIVDLLLINDKA VELELVAGEN STISAFNPTKYSSPSSVLLLFPNGT IVTLMAFTSHEVIVFSSNFIWASIG GVFAACLIIY IIIKMLCSFTPDVRYTLLNN
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: gH
• Synonyms: gH; Envelope glycoprotein H; gH
• UniProt ID: P13160

Gene Information

• Gene Name: gH
• Synonyms: gH; Envelope glycoprotein H; gH
• UniProt ID: P13160

Reviews

01/20/2022

Due to its high activity, the experiment can be successful in the first time, reducing the number of experiments.

11/17/2020

Fluorescent labeling works well and helps with imaging studies.

09/22/2020

The high yield and high purity facilitate our large-scale experiments.

Q&As

How to use growth hormone protein to treat disease?

In the treatment of certain diseases, such as growth hormone deficiency and dwarfism, replacement therapy can be achieved with the use of GH protein or its analogues to promote the growth and development of the body.

How can the regulation of GH protein gene expression be studied?

Studying the regulation of gene expression of GH protein can be achieved through the study of gene transcription, post-transcriptional modification, and translation. For example, it can be done by detecting the expression and activity of transcription factors, or by studying the effects of epigenetic modifications on GH gene expression.

Can growth hormone proteins interact with other hormones?

There are complex interactions between GH protein and other hormones. For example, GH protein can stimulate the secretion of insulin-like growth factor-1 (IGF-1), which in turn regulates GH secretion. In addition, GH can also interact with sex hormones to affect the body's growth and metabolic processes.

How can information from GH proteins be used to guide diagnosis or therapy in clinical practice?

In clinical practice, the diagnosis of diseases such as growth hormone deficiency, gigantism, and acromegaly can be guided by detecting the level or gene sequence of GH protein, as well as stimulation tests on GH protein. At the same time, based on the structural and functional characteristics of GH proteins, new drugs can be developed to treat these diseases.

What laboratory tests are used to diagnose growth hormone deficiency?

The diagnosis of growth hormone deficiency requires a series of laboratory tests, including GH stimulation test, insulin tolerance test, and serum insulin-like growth factor-1 (IGF-1) level. These tests can help your doctor determine whether you have a growth hormone deficiency.

Are the structure and function of GH proteins related?

The structure and function of GH proteins are closely related. Its specific amino acid sequence and spatial conformation determine its ability to bind to receptors and activate receptors. Therefore, the understanding of the structure and function of GH protein can help in the development of new drug designs and treatments.