Recombinant Full Length Human ABCE1 Protein, C-Flag-tagged
Cat.No. : | ABCE1-1570HFL |
Product Overview : | Recombinant Full Length Human ABCE1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 67.1 kDa |
AA Sequence : | MADKLTRIAIVNHDKCKPKKCRQEC KKSCPVVRMGKLCIEVTPQSKIAWI SETLCIGCGICIKKCPFGAL SIVNLPSNLEKETTHRYCANAFKLH RLPIPRPGEVLGLVGTNGIGKSTAL KILAGKQKPNLGKYDDPPDW QEILTYFRGSELQNYFTKILEDDLK AIIKPQYVDQIPKAAKGTVGSILDR KDETKTQAIVCQQLDLTHLK ERNVEDLSGGELQRFACAVVCIQKA DIFMFDEPSSYLDVKQRLKAAITIR SLINPDRYIIVVEHDLSVLD YLSDFICCLYGVPSAYGVVTMPFSV REGINIFLDGYVPTENLRFRDASLV FKVAETANEEEVKKMCMYKY PGMKKKMGEFELAIVAGEFTDSEIM VMLGENGTGKTTFIRMLAGRLKPDE GGEVPVLNVSYKPQKISPKS TGSVRQLLHEKIRDAYTHPQFVTDV MKPLQIENIIDQEVQTLSGGELQRV ALALCLGKPADVYLIDEPSA YLDSEQRLMAARVVKRFILHAKKTA FVVEHDFIMATYLADRVIVFDGVPS KNTVANSPQTLLAGMNKFLS QLEITFRRDPNNYRPRINKLNSIKD VEQKKSGNYFFLDDTRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | ABCE1 ATP binding cassette subfamily E member 1 [ Homo sapiens (human) ] |
Official Symbol : | ABCE1 |
Synonyms : | RLI; OABP; RLI1; ABC38; RNS4I; RNASEL1; RNASELI |
Gene ID : | 6059 |
mRNA Refseq : | NM_002940.3 |
Protein Refseq : | NP_002931.2 |
MIM : | 601213 |
UniProt ID : | P61221 |
Products Types
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◆ Lysates | ||
ABCE1-9145HCL | Recombinant Human ABCE1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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