Recombinant Full Length Human ACSS2 Protein, GST-tagged

• Cat.No.: ACSS2-814HF
• Product Overview: Human ACSS2 full-length ORF ( AAH98422.1, 1 a.a. - 606 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 94 kDa
• Protein Length: 606 amino acids
• AA Sequence: MKGATTNICY NVLDRNVHEK KLGDKVAFYW EGNEPGETTQ ITYHQLLVQV CQFSNVLRKQ GIQKGDRVAI YMPMIPELVV AMLACARIGA LHSIVFAGFS SESLCERILD SSCSLLITTD AFYRGEKLVN LKELADEALQ KCQEKGFPVR CCIVVKHLGR AELGMGDSTS QSPPIKRSCP DVQISWNQGI DLWWHELMQE AGDECEPEWC DAEDPLFILY TSGSTGKPKG VVHTVGGYML YVATTFKYVF DFHAEDVFWC TADIGWITGH SYVTYGPLAN GATSVLFEGI PTYPDVNRLW SIVDKYKVTK FYTAPTAIRL LMKFGDEPVT KHSRASLQVL GTVGEPINPE AWLWYHRVVG AQRCPIVDTF WQTETGGHML TPLPGATPMK PGSATFPFFG VAPAILNESG EELEGEAEGY LVFKQPWPGI MRTVYGNHER FETTYFKKFP GYYVTGDGCQ RDQDGYYWIT GRIDDMLNVS GHLLSTAEVE SALVEHEAVA EAAVVGHPHP VKGECLYCFV TLCDGHTFSP KLTEELKKQI REKIGPIATP DYIQNAPGLP KTRSGKIMRR VLRKIAQNDH DLGDMSTVAD PSVISHLFSH RCLTIQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACSS2 acyl-CoA synthetase short-chain family member 2 [ Homo sapiens ]
• Official Symbol: ACSS2
• Synonyms: ACSS2; acyl-CoA synthetase short-chain family member 2; ACAS2, acetyl Coenzyme A synthetase 2 (ADP forming); acetyl-coenzyme A synthetase, cytoplasmic; AceCS; ACS; ACSA; dJ1161H23.1; acetate thiokinase; acetate-CoA ligase; acyl-activating enzyme; cytoplasmic acetyl-coenzyme A synthetase; acetyl-Coenzyme A synthetase 2 (ADP forming); ACAS2; ACECS; DKFZp762G026
• Gene ID: 55902
• mRNA Refseq: NM_001076552
• Protein Refseq: NP_001070020
• MIM: 605832
• UniProt ID: Q9NR19