Recombinant Full Length Human APOBEC3G Protein, C-Flag-tagged

• Cat.No.: APOBEC3G-547HFL
• Product Overview: Recombinant Full Length Human APOBEC3G Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene catalyzes site-specific deamination of both RNA and single-stranded DNA. The encoded protein has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 46.2 kDa
• AA Sequence: MKPHFRNTVERMYRDTFSYNFYNRP ILSRRNTVWLCYEVKTKGPSRPPLD AKIFRGQVYSELKYHPEMRF FHWFSKWRKLHRDQEYEVTWYISWS PCTKCTRDMATFLAEDPKVTLTIFV ARLYYFWDPDYQEALRSLCQ KRDGPRATMKIMNYDEFQHCWSKFV YSQRELFEPWNNLPKYYILLHIMLG EILRHSMDPPTFTFNFNNEP WVRGRHETYLCYEVERMHNDTWVLL NQRRGFLCNQAPHKHGFLEGRHAEL CFLDVIPFWKLDLDQDYRVT CFTSWSPCFSCAQEMAKFISKNKHV SLCIFTARIYDDQGRCQEGLRTLAE AGAKISIMTYSEFKHCWDTF
  VDHQGCPFQPWDGLDEHSQDLSGRL RAILQNQENTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: APOBEC3G apolipoprotein B mRNA editing enzyme catalytic subunit 3G [ Homo sapiens (human) ]
• Official Symbol: APOBEC3G
• Synonyms: A3G; ARCD; ARP9; ARP-9; CEM15; CEM-15; MDS019; bK150C2.7; dJ494G10.1
• Gene ID: 60489
• mRNA Refseq: NM_021822.4
• Protein Refseq: NP_068594.1
• MIM: 607113
• UniProt ID: Q9HC16