Recombinant Full Length Human ARHGEF10L Protein, C-Flag-tagged

• Cat.No.: ARHGEF10L-1832HFL
• Product Overview: Recombinant Full Length Human ARHGEF10L Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 140.2 kDa
• AA Sequence: MASSNPPPQPAIGDQLVPGVPGPSS EAEDDPGEAFEFDDSDDEEDTSAAL GVPSLAPERDTDPPLIHLDS IPVTDPDPAAAPPGTGVPAWVSNGD AADAAFSGARHSSWKRKSSRRIDRF TFPALEEDVIYDDVPCESPD AHQPGAERNLLYEDAHRAGAPRQAE DLGWSSSEFESYSEDSGEEAKPEVE VEPAKHRVSFQPKLSPDLTR LKERYARTKRDILALRVGGRDMQEL KHKYDCKMTQLMKAAKSGTKDGLEK TRMAVMRKVSFLHRKDVLGD SEEEDMGLLEVSVSDIKPPAPELGP MPEGLSPQQVVRRHILGSIVQSEGS YVESLKRILQDYRNPLMEME PKALSARKCQVVFFRVKEILHCHSM FQIALSSRVAEWDSTEKIGDLFVAS FSKSMVLDVYSDYVNNFTSA MSIIKKACLTKPAFLEFLKRRQVCS PDRVTLYGLMVKPIQRFPQFILLLQ DMLKNTPRGHPDRLSLQLAL TELETLAEKLNEQKRLADQVAEIQQ LTKSVSDRSSLNKLLTSGQRQLLLC ETLTETVYGDRGQLIKSKER RVFLLNDMLVCANINFKPANHRGQL EISSLVPLGPKYVVKWNTALPQVQV VEVGQDGGTYDKDNVLIQHS GAKKASASGQAQNKVYLGPPRLFQE LQDLQKDLAVVEQITLLISTLHGTY QNLNMTVAQDWCLALQRLMR VKEEEIHSANKCRLRLLLPGKPDKS GRPISFMVVFITPNPLSKISWVNRL HLAKIGLREENQPGWLCPDE DKKSKAPFWCPILACCIPAFSSRAL SLQLGALVHSPVNCPLLGFSAVSTS LPQGYLWVGGGQEGAGGQVE IFSLNRPSPRTVKSFPLAAPVLCME YIPELEEEAESRDESPTVADPSATV HPTICLGLQDGSILLYSSVD TGTQCLVSCRSPGLQPVLCLRHSPF HLLAGLQDGTLAAYPRTSGGVLWDL ESPPVCLTVGPGPVRTLLSL EDAVWASCGPRVTVLEATTLQPQQS FEAHQDEAVSVTHMVKAGSGVWMAF SSGTSIRLFHTETLEHLQEI NIATRTTFLLPGQKHLCVTSLLICQ GLLWVGTDQGVIVLLPVPRLEGIPK ITGKGMVSLNGHCGPVAFLA VATSILAPDILRSDQEEAEGPRAEE DKPDGQAHEPMPDSHVGRELTRKKG ILLQYRLRSTAHLPGPLLSM REPAPADGAALEHSEEDGSIYEMAD DPDIWVRSRPCARDAHRKEICSVAI ISGGQGYRNFGSALGSSGRQ APCGETDSTLLIWQVPLML TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: ARHGEF10L Rho guanine nucleotide exchange factor 10 like [ Homo sapiens (human) ]
• Official Symbol: ARHGEF10L
• Synonyms: GrinchGEF
• Gene ID: 55160
• mRNA Refseq: NM_018125.4
• Protein Refseq: NP_060595.3
• MIM: 612494
• UniProt ID: Q9HCE6