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Recombinant Full Length Human ARNTL2 Protein, GST-tagged

Cat.No. : ARNTL2-1251HF
Product Overview : Human ARNTL2 full-length ORF (AAH00172.3, 1 a.a. - 579 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 90.09 kDa
Protein Length : 579 amino acids
AA Sequence : MGKVLREENQ CIAPVVSSRV SPGTRPTAMG SFSSHMTEFP RKRKGSDSDP SQEAHSQTEK RRRDKMNNLI EELSAMIPQC NPMARKLDKL TVLRMAVQHL RSLKGLTNSY VGSNYRPSFL QDNELRHLIL KTAEGFLFVV GCERGKILFV SKSVSKILNY DQASLTGQSL FDFLHPKDVA KVKEQLSSFD ISPREKLIDA KTGLQVHSNL HAGRTRVYSG SRRSFFCRIK SCKISVKEEH GCLPNSKKKE HRKFYTIHCT GYLRSWPPNI VGMEEERNSK KDNSNFTCLV AIGRLQPYIV PQNSGEINVK PTEFITRFAV NGKFVYVDQR ATAILGYLPQ ELLGTSCYEY FHQDDHNNLT DKHKAVLQSK EKILTDSYKF RAKDGSFVTL KSQWFSFTNP WTKELEYIVS VNTLVLGHSE PGEASFLPCS SQSSEESSRQ SCMSVPGMST GTVLGAGSIG TDIANEILDL QRLQSSSYLD DSSPTGLMKD THTVNCRSMS NKELFPPSPS EMGELEATRQ NQSTVAVHSH EPLLSDGAQL DFDALCDNDD TAMAAFMNYL EAEGGLGDPG DFSDIQWTL
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 [ Homo sapiens ]
Official Symbol : ARNTL2
Synonyms : ARNTL2; aryl hydrocarbon receptor nuclear translocator-like 2; aryl hydrocarbon receptor nuclear translocator-like protein 2; bHLHe6; BMAL2; CLIF; MOP9; PASD9; CYCLE-like factor; member of PAS protein 9; transcription factor BMAL2; brain and muscle ARNT-like 2; PAS domain-containing protein 9; basic-helix-loop-helix-PAS protein MOP9; class E basic helix-loop-helix protein 6; MGC149671; MGC149672
Gene ID : 56938
mRNA Refseq : NM_001248002
Protein Refseq : NP_001234931
MIM : 614517
UniProt ID : Q8WYA1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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