Recombinant Full Length Human BMP2K Protein, C-Flag-tagged

• Cat.No.: BMP2K-1298HFL
• Product Overview: Recombinant Full Length Human BMP2K Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 129 kDa
• AA Sequence: MKKFSRMPKSEGGSGGGAAGGGAGG AGAGAGCGSGGSSVGVRVFAVGRHQ VTLEESLAEGGFSTVFLVRT HGGIRCALKRMYVNNMPDLNVCKRE ITIMKELSGHKNIVGYLDCAVNSIS DNVWEVLILMEYCRAGQVVN QMNKKLQTGFTEPEVLQIFCDTCEA VARLHQCKTPIIHRDLKVENILLND GGNYVLCDFGSATNKFLNPQ KDGVNVVEEEIKKYTTLSYRAPEMI NLYGGKPITTKADIWALGCLLYKLC FFTLPFGESQVAICDGNFTI PDNSRYSRNIHCLIRFMLEPDPEHR PDIFQVSYFAFKFAKKDCPVSNINN SSIPSALPEPMTASEAAARK SQIKARITDTIGPTETSIAPRQRPK ANSATTATPSVLTIQSSATPVKVLA PGEFGNHRPKGALRPGNGPE ILLGQGPPQQPPQQHRVLQQLQQGD WRLQQLHLQHRHPHQQQQQQQQQQQ QQQQQQQQQQQQQQQQHHHH HHHHLLQDAYMQQYQHATQQQQMLQ QQFLMHSVYQPQPSASQYPTMMPQY QQAFFQQQMLAQHQPSQQQA SPEYLTSPQEFSPALVSYTSSLPAQ VGTIMDSSYSANRSVADKEAIANFT NQKNISNPPDMSGWNPFGED NFSKLTEEELLDREFDLLRSNRLEE RASSDKNVDSLSAPHNHPPEDPFGS VPFISHSGSPEKKAEHSSIN QENGTANPIKNGKTSPASKDQRTGK KTSVQGQVQKGNDESESDFESDPPS PKSSEEEEQDDEEVLQGEQG DFNDDDTEPENLGHRPLLMDSEDEE EEEKHSSDSDYEQAKAKYSDMSSVY RDRSGSGPTQDLNTILLTSA QLSSDVAVETPKQEFDVFGAVPFFA VRAQQPQQEKNEKNLPQHRFPAAGL EQEEFDVFTKAPFSKKVNVQ ECHAVGPEAHTIPGYPKSVDVFGST PFQPFLTSTSKSESNEDLFGLVPFD EITGSQQQKVKQRSLQKLSS RQRRTKQDMSKSNGKRHHGTPTSTK KTLKPTYRTPERARRHKKVGRRDSQ SSNEFLTISDSKENISVALT DGKDRGNVLQPEESLLDPFGAKPFH SPDLSWHPPHQGLSDIRADHNTVLP GRPRQNSLHGSFHSADVLKM
  DDFGAVPFTELVVQSITPHQSQQSQ PVELDPFGAAPFPSKQTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protein Kinase

Gene Information

• Gene Name: BMP2K BMP2 inducible kinase [ Homo sapiens (human) ]
• Official Symbol: BMP2K
• Synonyms: BIKE; HRIHFB2017
• Gene ID: 55589
• mRNA Refseq: NM_198892.2
• Protein Refseq: NP_942595.1
• MIM: 617648
• UniProt ID: Q9NSY1