Recombinant Full Length Human CACNB1 Protein, GST-tagged

• Cat.No.: CACNB1-2961HF
• Product Overview: Human CACNB1 full-length ORF (NP_000714.3, 1 a.a. - 598 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 92.1 kDa
• Protein Length: 598 amino acids
• AA Sequence: MVQKTSMSRGPYPPSQEIPMEVFDP SPQGKYSKRKGRFKRSDGSTSSDTT SNSFVRQGSAESYTSRPSDSDVSLE EDREALRKEAERQALAQLEKAKTKP VAFAVRTNVGYNPSPGDEVPVQGVA ITFEPKDFLHIKEKYNNDWWIGRLV KEGCEVGFIPSPVKLDSLRLLQEQK LRQNRLGSSKSGDNSSSSLGDVVTG TRRPTPPASAKQKQKSTEHVPPYDV VPSMRPIILVGPSLKGYEVTDMMQK ALFDFLKHRFDGRISITRVTADISL AKRSVLNNPSKHIIIERSNTRSSLA EVQSEIERIFELARTLQLVALDADT INHPAQLSKTSLAPIIVYIKITSPK VLQRLIKSRGKSQSKHLNVQIAASE KLAQCPPEMFDIILDENQLEDACEH LAEYLEAYWKATHPPSSTPPNPLLN RTMATAALAASPAPVSNLQGPYLAS GDQPLERATGEHASMHEYPGELGQP PGLYPSSHPPGRAGTLRALSRQDTF DADTPGSRNSAYTELGDSCVDMETD PSEGPGLGDPAGGGTPPARQGSWED EEEDYEEELTDNRNRGRNKARYCAE GGGPVLGRNKNELEGWGRGVYIR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CACNB1 calcium channel, voltage-dependent, beta 1 subunit [ Homo sapiens ]
• Official Symbol: CACNB1
• Synonyms: CACNB1; calcium channel, voltage-dependent, beta 1 subunit; CACNLB1; voltage-dependent L-type calcium channel subunit beta-1; calcium channel, L type, beta 1 polypeptide; calcium channel voltage-dependent subunit beta 1; dihydropyridine-sensitive L-type, calcium channel beta-1 subunit; CAB1; CCHLB1; MGC41896
• Gene ID: 782
• mRNA Refseq: NM_000723
• Protein Refseq: NP_000714
• MIM: 114207
• UniProt ID: Q02641