Recombinant Full Length Human CALD1 Protein

• Cat.No.: CALD1-46HF
• Product Overview: Recombinant full length protein, corresponding to amino acids 1-538 of Human Caldesmon, with an N-terminal proprietary tag, predicted MWt 85.25 kDa.

Specification

• Description: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 85.250kDa inclusive of tags
• Protein Length: 538 amino acids
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents: 0.3% Glutathione, 0.79% Tris HCl.

Gene Information

• Gene Name: CALD1 caldesmon 1 [ Homo sapiens ]
• Official Symbol: CALD1
• Synonyms: CALD1; caldesmon 1; caldesmon; CDM; H CAD; LCAD
• Gene ID: 800
• mRNA Refseq: NM_004342
• Protein Refseq: NP_004333
• MIM: 114213
• UniProt ID: Q05682