Recombinant Full Length Human CPT1A Protein, GST-tagged

• Cat.No.: CPT1A-2228HF
• Product Overview: Human CPT1A full-length ORF ( NP_001867.2, 1 a.a. - 773 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 114.8 kDa
• Protein Length: 773 amino acids
• AA Sequence: MAEAHQAVAFQFTVTPDGIDLRLSH EALRQIYLSGLHSWKKKFIRFKNGI ITGVYPASPSSWLIVVVGVMTTMYA KIDPSLGIIAKINRTLETANCMSSQ TKNVVSGVLFGTGLWVALIVTMRYS LKVLLSYHGWMFTEHGKMSRATKIW MGMVKIFSGRKPMLYSFQTSLPRLP VPAVKDTVNRYLQSVRPLMKEEDFK RMTALAQDFAVGLGPRLQWYLKLKS WWATNYVSDWWEEYIYLRGRGPLMV NSNYYAMDLLYILPTHIQAARAGNA IHAILLYRRKLDREEIKPIRLLGST IPLCSAQWERMFNTSRIPGEETDTI QHMRDSKHIVVYHRGRYFKVWLYHD GRLLKPREMEQQMQRILDNTSEPQP GEARLAALTAGDRVPWARCRQAYFG RGKNKQSLDAVEKAAFFVTLDETEE GYRSEDPDTSMDSYAKSLLHGRCYD RWFDKSFTFVVFKNGKMGLNAEHSW ADAPIVAHLWEYVMSIDSLQLGYAE DGHCKGDINPNIPYPTRLQWDIPGE CQEVIETSLNTANLLANDVDFHSFP FVAFGKGIIKKCRTSPDAFVQLALQ LAHYKDMGKFCLTYEASMTRLFREG RTETVRSCTTESCDFVRAMVDPAQT VEQRLKLFKLASEKHQHMYRLAMTG SGIDRHLFCLYVVSKYLAVESPFLK EVLSEPWRLSTSQTPQQQVELFDLE NNPEYVSSGGGFGPVADDGYGVSYI LVGENLINFHISSKFSCPETDSHRF GRHLKEAMTDIITLFGLSSNSKK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CPT1A carnitine palmitoyltransferase 1A (liver) [ Homo sapiens ]
• Official Symbol: CPT1A
• Synonyms: CPT1A; carnitine palmitoyltransferase 1A (liver); CPT1; carnitine O-palmitoyltransferase 1, liver isoform; CPT1 L; L CPT1; CPT I; CPTI-L; carnitine palmitoyltransferase I, liver; carnitine O-palmitoyltransferase I, liver isoform; CPT1-L; L-CPT1
• Gene ID: 1374
• mRNA Refseq: NM_001031847
• Protein Refseq: NP_001027017
• MIM: 600528
• UniProt ID: P50416