Recombinant Full Length Human CROT Protein, GST-tagged

• Cat.No.: CROT-2092HF
• Product Overview: Human CROT full-length ORF ( NP_066974.2, 1 a.a. - 612 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 96.6 kDa
• Protein length: 612 amino acids
• AA Sequence: MENQLAKSTEERTFQYQDSLPSLPV PSLEESLKKYLESVKPFANQEEYKK TEEIVQKFQSGIGEKLHQKLLERAK GKRNWLEEWWLNVAYLDVRIPSQLN VNFAGPAAHFEHYWPPKEGTQLERG SITLWHNLNYWQLLRKEKVPVHKVG NTPLDMNQFRMLFSTCKVPGITRDS IMNYFRTESEGRSPNHIVVLCRGRA FVFDVIHEGCLVTPPELLRQLTYIH KKCHSEPDGPGIAALTSEERTRWAK AREYLIGLDPENLALLEKIQSSLLV YSMEDSSPHVTPEDYSEIIAAILIG DPTVRWGDKSYNLISFSNGVFGCNC DHAPFDAMIMVNISYYVDEKIFQNE GRWKGSEKVRDIPLPEELIFIVDEK VLNDINQAKAQYLREASDLQIAAYA FTSFGKKLTKNKMLHPDTFIQLALQ LAYYRLHGHPGCCYETAMTRHFYHG RTETMRSCTVEAVRWCQSMQDPSVN LRERQQKMLQAFAKHNKMMKDCSAG KGFDRHLLGLLLIAKEEGLPVPELF TDPLFSKSGGGGNFVLSTSLVGYLR VQGVVVPMVHNGYGFFYHIRDDRFV VACSAWKSCPETDAEKLVQLTFCAF HDMIQLMNSTHL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CROT carnitine O-octanoyltransferase [ Homo sapiens ]
• Official Symbol: CROT
• Synonyms: CROT; carnitine O-octanoyltransferase; peroxisomal carnitine O-octanoyltransferase; COT; peroxisomal carnitine acyltransferase
• Gene ID: 54677
• mRNA Refseq: NM_001143935
• Protein Refseq: NP_001137407
• MIM: 606090
• UniProt ID: Q9UKG9