Recombinant Full Length Human CRTC1 Protein, C-Flag-tagged

• Cat.No.: CRTC1-1443HFL
• Product Overview: Recombinant Full Length Human CRTC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 67.1 kDa
• AA Sequence: MATSNNPRKFSEKIALHNQKQAEET AAFEEVMKDLSLTRAARLQLQKSQY LQLGPSRGQYYGGSLPNVNQ IGSGTMDLPFQTPFQSSGLDTSRTT RHHGLVDRVYRERGRLGSPHRRPLS VDKHGRQADSCPYGTMYLSP PADTSWRRTNSDSALHQSTMTPTQP ESFSSGSQDVHQKRVLLLTVPGMEE TTSEADKNLSKQAWDTKKTG SRPKSCEVPGINIFPSADQENTTAL IPATHNTGGSLPDLTNIHFPSPLPT PLDPEEPTFPALSSSSSTGN LAANLTHLGIGGAGQGMSTPGSSPQ HRPAGVSPLSLSTEARRQQASPALS PLSPITQAVAMDALSLEQQL PYAFFTQAGSQQPPPQPQPPPPPPP ASQQPPPPPPPQAPVRLPPGGPLLP SASLTRGPQPPPLAVTVPSS LPQSPPENPGQPSMGIDIASAPALQ QYRTSAGSPANQSPTSPVSNQGFSP GSSPQHTSTLGSVFGDAYYE QQMAARQANALSHQLEQFNMMENAI SSSSLYSPGSTLNYSQAAMMGLTGS HGSLPDSQQLGYASHSGIPN IILTVTGESPPSLSKELTSSLAGVG DVSFDSDSQFPLDELKIDPLTLDGL HMLNDPDMVLADPATEDTFR
  MDRLSGPTRTRRLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors

Gene Information

• Gene Name: CRTC1 CREB regulated transcription coactivator 1 [ Homo sapiens (human) ]
• Official Symbol: CRTC1
• Synonyms: MAML2; MECT1; Mam-2; TORC1; TORC-1; WAMTP1
• Gene ID: 23373
• mRNA Refseq: NM_015321.3
• Protein Refseq: NP_056136.2
• MIM: 607536
• UniProt ID: Q6UUV9