Recombinant Full Length Human DDR1 Protein
| Cat.No. : | DDR1-2469HF |
| Product Overview : | Human DDR1 full-length ORF (NP_001945.3) recombinant protein without tag. |
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| Description : | Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |
| Source : | In Vitro Cell Free System |
| Species : | Human |
| Tag : | GST |
| Form : | Liquid |
| Molecular Mass : | 97.2 kDa |
| Protein Length : | 913 amino acids |
| AA Sequence : | MGPEALSSLLLLLLVASGDADMKGH FDPAKCRYALGMQDRTIPDSDISAS SSWSDSTAARHSRLESSDGDGAWCP AGSVFPKEEEYLQVDLQRLHLVALV GTQGRHAGGLGKEFSRSYRLRYSRD GRRWMGWKDRWGQEVISGNEDPEGV VLKDLGPPMVARLVRFYPRADRVMS VCLRVELYGCLWRDGLLSYTAPVGQ TMYLSEAVYLNDSTYDGHTVGGLQY GGLGQLADGVVGLDDFRKSQELRVW PGYDYVGWSNHSFSSGYVEMEFEFD RLRAFQAMQVHCNNMHTLGARLPGG VECRFRRGPAMAWEGEPMRHNLGGN LGDPRARAVSVPLGGRVARFLQCRF LFAGPWLLFSEISFISDVVNNSSPA LGGTFPPAPWWPPGPPPTNFSSLEL EPRGQQPVAKAEGSPTAILIGCLVA IILLLLLIIALMLWRLHWRRLLSKA ERRVLEEELTVHLSVPGDTILINNR PGPREPPPYQEPRPRGNPPHSAPCV PNGSAYSGDYMEPEKPGAPLLPPPP QNSVPHYAEADIVTLQGVTGGNTYA VPALPPGAVGDGPPRVDFPRSRLRF KEKLGEGQFGEVHLCEVDSPQDLVS LDFPLNVRKGHPLLVAVKILRPDAT KNARNDFLKEVKIMSRLKDPNIIRL LGVCVQDDPLCMITDYMENGDLNQF LSAHQLEDKAAEGAPGDGQAAQGPT ISYPMLLHVAAQIASGMRYLATLNF VHRDLATRNCLVGENFTIKIADFGM SRNLYAGDYYRVQGRAVLPIRWMAW ECILMGKFTTASDVWAFGVTLWEVL MLCRAQPFGQLTDEQVIENAGEFFR DQGRQVYLSRPPACPQGLYELMLRC WSRESEQRPPFSQLHRFLAEDALNT V |
| Applications : | Antibody Production Functional Study Compound Screening |
| Usage : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
| Gene Name : | DDR1 discoidin domain receptor tyrosine kinase 1 [ Homo sapiens ] |
| Official Symbol : | DDR1 |
| Synonyms : | DDR1; discoidin domain receptor tyrosine kinase 1; CAK, discoidin domain receptor family, member 1 , EDDR1, NEP, NTRK4, PTK3A; epithelial discoidin domain-containing receptor 1; CD167; RTK6; tyrosine kinase DDR; cell adhesion kinase; mammary carcinoma kinase 10; tyrosine-protein kinase CAK; protein-tyrosine kinase RTK-6; neuroepithelial tyrosine kinase; PTK3A protein tyrosine kinase 3A; CD167 antigen-like family member A; neurotrophic tyrosine kinase, receptor, type 4; CAK; DDR; NEP; HGK2; PTK3; TRKE; EDDR1; MCK10; NTRK4; PTK3A; |
| Gene ID : | 780 |
| mRNA Refseq : | NM_001202521 |
| Protein Refseq : | NP_001189450 |
| MIM : | 600408 |
| UniProt ID : | Q08345 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (6)
Write a reviewAQP12B protein has been extensively studied and characterized, allowing researchers to confidently integrate it into their experimental workflows.
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Their knowledgeable team is readily available to address any questions or concerns, guaranteeing a smooth experimental process.
Its unique properties and functions make it an essential component in investigating various biological processes and molecular mechanisms.
Its purity and integrity are of the highest standard, ensuring reliable and reproducible results in my research.
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