Recombinant Full Length Human DKC1 Protein, GST-tagged
Cat.No. : | DKC1-570HF |
Product Overview : | Recombinant full length Human DKC1(1 a.a. - 514 a.a.), fussed with GST at N-terminal, was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 84.1 kDa |
Protein Length : | 514 amino acids |
AA Sequence : | MADAEVIILP KKHKKKKERK SLPEEDVAEI QHAEEFLIKP ESKVAKLDTS QWPLLLKNFD KLNVRTTHYT PLACGSNPLK REIGDYIRTG FINLDKPSNP SSHEVVAWIR RILRVEKTGH SGTLDPKVTG CLIVCIERAT RLVKSQQSAG KEYVGIVRLH NAIEGGTQLS RALETLTGAL FQRPPLIAAV KRQLRVRTIY ESKMIEYDPE RRLGIFWVSC EAGTYIRTLC VHLGLLLGVG GQMQELRRVR SGVMSEKDHM VTMHDVLDAQ WLYDNHKDES YLRRVVYPLE KLLTSHKRLV MKDSAVNAIC YGAKIMLPGV LRYEDGIEVN QEIVVITTKG EAICMAIALM TTAVISTCDH GIVAKIKRVI MERDTYPRKW GLGPKASQKK LMIKQGLLDK HGKPTDSTPA TWKQEYVDYS ESAKKEVVAE VVKAPQVVAE AAKTAKRKRE SESESDETPP AAPQLIKKEK KKSKKDKKAK AGLESGAEPG DGDSDTTKKK KKKKKAKEVE LVSE |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | DKC1 dyskeratosis congenita 1, dyskerin [ Homo sapiens ] |
Official Symbol : | DKC1 |
Synonyms : | DKC1; dyskeratosis congenita 1, dyskerin; DKC; H/ACA ribonucleoprotein complex subunit 4; dyskerin; NAP57; NOLA4; XAP101; CBF5 homolog; cbf5p homolog; snoRNP protein DKC1; nucleolar protein NAP57; nucleolar protein family A member 4; nopp140-associated protein of 57 kDa; CBF5; DKCX; FLJ97620; |
Gene ID : | 1736 |
mRNA Refseq : | NM_001363 |
Protein Refseq : | NP_001354 |
MIM : | 300126 |
UniProt ID : | O60832 |
Products Types
◆ Recombinant Protein | ||
Dkc1-687R | Recombinant Rat Dkc1 Protein, His-tagged | +Inquiry |
DKC1-1097R | Recombinant Rhesus Macaque DKC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DKC1-685H | Recombinant Human DKC1 Protein, His-tagged | +Inquiry |
DKC1-1533R | Recombinant Rat DKC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Dkc1-686M | Recombinant Mouse Dkc1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
DKC1-6916HCL | Recombinant Human DKC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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