Recombinant Full Length Human ECM1 Protein, GST-tagged

• Cat.No.: ECM1-4172HF
• Product Overview: Human ECM1 full-length ORF ( AAH23505, 1 a.a. - 540 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 85.14 kDa
• Protein Length: 540 amino acids
• AA Sequence: MGTTARAALVLTYLAVASAASEGGF TATGQRQLRPEHFQEVGYAAPPSPP LSRSLPMDHPDSSQHGPPFEGQSQV QPPPSQEATPLQQEKLLPAQLPAEK EVGPPLPQEAVPLQKELPSLQHPNE QKEGMPAPFGDQSHPEPESWNAAQH CQQDRSQGGWGHRLDGFPPGRPSPD NLNQICLPNRQHVVYGPWNLPQSSY SHLTRQGETLNFLEIGYSRCCHCRS HTNRLECAKLVWEEAMSRFCEAEFS VKTRPHWCCTRQGEARFSCFQEEAP QPHYQLRACPSHQPDISSGLELPFP PGVPTLDNIKNICHLRRFRSVPRNL PATDPLQRELLALIQLEREFQRCCR QGNNHTCTWKAWEDTLDKYCDREYA VKTHHHLCCRHPPSPTRDECFARRA PYPNYDRDILTIDISRATPNLMGHL CGNQRVLTKHKHIPGLIHNMTARCC DLPFPEQACCAEEEKLTFINDLCGP RRNIWRDPALCCYLSPGDEQVNCFN INYLRNVALVSGDTENAKGQGEQGS TGGTNISSTSEPKEK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ECM1 extracellular matrix protein 1 [ Homo sapiens ]
• Official Symbol: ECM1
• Synonyms: ECM1; extracellular matrix protein 1; secretory component p85
• Gene ID: 1893
• mRNA Refseq: NM_001202858
• Protein Refseq: NP_001189787
• MIM: 602201
• UniProt ID: Q16610