Recombinant Full Length Human exosome component 9 Protein, His tagged

• Cat.No.: EXOSC9-0732HFL
• Product Overview: Full-length cDNA coding for the human PM/Scl 75c-ß isoform fused to a hexahistidine purification tag was expressed in baculovirus (Autographa californica multiple nuclear polyhedrosis virus; AcMNPV) infection of Spodoptera frugiperda Sf9 insect cells.

Specification

• Species: Human
• Source: Baculovirus
• Tag: His
• Protein Length: 1-439 aa
• Description: This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants.
• Tag: His
• Calculated isoelectric point: pH 5.46
• Molecular Mass: 52 kDa
• Immunological function: Binds IgG-type human auto-antibodies.
• Immunological tests: Immunodot analyses with positive/negative samples.
• Biochemical tests: SDS-PAGE (purity > 80%); Western blot with i: anti-PM/Scl 75 auto-antibody-positive sample; ii: monoclonal anti-His-tag antibody.
• Storage: At -70 centigrade or below. Repeated freeze/thaw cycles should be avoided.
• Storage Buffer: Neutral to slightly alkaline pH and 0.02% SDS.

Gene Information

• Gene Name: EXOSC9 exosome component 9 [ Homo sapiens (human) ]
• Official Symbol: EXOSC9
• Synonyms: EXOSC9; exosome component 9; PMSCL1, polymyositis/scleroderma autoantigen 1, 75kDa; exosome complex component RRP45; p5; p6; PM/Scl 75; polymyositis/scleroderma autoantigen 1 (75kD); RRP45; Rrp45p; autoantigen PM/Scl 1; PMSCL autoantigen, 75kD; exosome complex exonuclease RRP45; polymyositis/scleroderma autoantigen 1, 75kDa; P75 polymyositis-scleroderma overlap syndrome associated autoantigen; P75 polymyositis-scleroderma overlap syndrome-associated autoantigen; PMSCL1; PM/Scl-75
• Gene ID: 5393
• mRNA Refseq: NM_001034194
• Protein Refseq: NP_001029366
• MIM: 606180
• UniProt ID: Q06265