Recombinant Full Length Human FANCG Protein

• Cat.No.: FANCG-164HF
• Product Overview: Recombinant full length Human FANCG with a N terminal proprietary tag; Predicted MWt 94.53 kDa including the tag.

Specification

• Description: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 94.530kDa inclusive of tags
• Protein Length: 622 amino acids
• AA Sequence: MSRQTTSVGSSCLDLWREKNDRLVRQAKVAQNSGLTLR RQQLAQDALEGLRGLLHSLQGLPAAVPVLPLELTVTCNFI ILRASLAQGFTEDQAQDIQRSLERVLETQEQQGPRLEQGL RELWDSVLRASCLLPELLSALHRLVGLQAALWLSADRLGD LALLLETLNGSQSGASKDLLLLLKTWSPPAEELDAPLTLQ DAQGLKDVLLTAFAYRQGLQELITGNPDKALSSLHEAASG LCPRPVLVQVYTALGSCHRKMGNPQRALLYLVAALKEGSA WGPPLLEASRLYQQLGDTTAELESLELLVEALNVPCSSKA PQFLIEVELLLPPPDLASPLHCGTQSQTKHILASRCLQTG RAGDAAEHYLDLLALLLDSSEPRFSPPPSPPGPCMPEVFL EAAVALIQAGRAQDALTLCEELLSRTSSLLPKMSRLWEDA RKGTKELPYCPLWVSATHLLQGQAWVQLGAQKVAISEFSR CLELLFRATPEEKEQGAAFNCEQGCKSDAALQQLRAAALI SRGLEWVASGQDTKALQDFLLSVQMCPGNRDTYFHLLQTL KRLDRRDEATALWWRLEAQTKGSHEDALWSLPLYLESYLS WIRPSDRDAFLEEFRTSLPKSCDL
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: FANCG Fanconi anemia, complementation group G [ Homo sapiens ]
• Official Symbol: FANCG
• Synonyms: FANCG; Fanconi anemia, complementation group G; XRCC9; Fanconi anemia group G protein; DNA repair protein XRCC9; FAG; X ray repair complementing defective repair in Chinese hamster cells 9; X ray repair; complementing defective; in Chinese hamster
• Gene ID: 2189
• mRNA Refseq: NM_004629
• Protein Refseq: NP_004620
• MIM: 602956
• UniProt ID: O15287