Recombinant Full Length Human FBXO42 Protein, C-Flag-tagged

• Cat.No.: FBXO42-1265HFL
• Product Overview: Recombinant Full Length Human FBXO42 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 77.7 kDa
• AA Sequence: MASSSDSEDDSFMAVDQEETVLEGT MDQDEEPHPVLEAEETRHNRSMSEL PEEVLEYILSFLSPYQEHKT AALVCKQWYRLIKGVAHQCYHGFMK AVQEGNIQWESRTYPYPGTPITQRF SHSACYYDANQSMYVFGGCT QSSCNAAFNDLWRLDLNSKEWIRPL ASGSYPSPKAGATLVVYKDLLVLFG GWTRPSPYPLHQPERFFDEI HTYSPSKNWWNCIVTTHGPPPMAGH SSCVIDDKMIVFGGSLGSRQMSNDV WVLDLEQWAWSKPNISGPSP HPRGGQSQIVIDDATILILGGCGGP NALFKDAWLLHMHSGPWAWQPLKVE NEEHGAPELWCHPACRVGQC VVVFSQAPSGRAPLSPSLNSRPSPI SATPPALVPETREYRSQSPVRSMDE APCVNGRWGTLRPRAQRQTP SGSREGSLSPARGDGSPILNGGSLS PGTAAVGGSSLDSPVQAISPSTPSA PEGYDLKIGLSLAPRRGSLP DQKDLRLGSIDLNWDLKPASSSNPM DGMDNRTVGGSMRHPPEQTNGVHTP PHVASALAGAVSPGALRRSL EAIKAMSSKGPSASAALSPPLGSSP GSPGSQSLSSGETVPIPRPGPAQGD GHSLPPIARRLGHHPPQSLN VGKPLYQSMNCKPMQMYVLDIKDTK EKGRVKWKVFNSSSVVGPPETSLHT VVQGRGELIIFGGLMDKKQN
  VKYYPKTNALYFVRAKRTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: FBXO42 F-box protein 42 [ Homo sapiens (human) ]
• Official Symbol: FBXO42
• Synonyms: JFK; Fbx42
• Gene ID: 54455
• mRNA Refseq: NM_018994.3
• Protein Refseq: NP_061867.1
• MIM: 609109
• UniProt ID: Q6P3S6