Recombinant Full Length Human GBA Protein

Species :	Human
Source :	In Vitro Cell Free System
Protein Length :	536 amino acids
Description :	This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Form :	Liquid
Molecular Mass :	84.700kDa inclusive of tags
AA Sequence :	MEFSSPSREECPKPLSRVSIIAGSLTGLLLLQAVSWASGA RPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYE STRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGF GGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRV PMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLI HRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQP GDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLL SGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLML DDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAK ATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGM QYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSP IIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQK NDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLE TISPGYSIHTYLWRRQ
Purity :	Proprietary Purification
Storage :	Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
Storage Buffer :	pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Name	GBA glucosidase, beta, acid [ Homo sapiens ]
Official Symbol	GBA
Synonyms	GBA; glucosidase, beta, acid; GLUC, glucosidase, beta; acid (includes glucosylceramidase) , glucosylceramidase; glucosylceramidase; GBA1
Gene ID	2629
mRNA Refseq	NM_000157
Protein Refseq	NP_000148
MIM	606463
UniProt ID	P04062