Recombinant Full Length Human GBA Protein, GST-tagged

• Cat.No.: GBA-5511HF
• Product Overview: Human GBA full-length ORF ( AAH03356, 1 a.a. - 536 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 84.70 kDa
• Protein Length: 536 amino acids
• AA Sequence: MEFSSPSREECPKPLSRVSIIAGSL TGLLLLQAVSWASGARPCIPKSFGY SSVVCVCNATYCDSFDPPTFPALGT FSRYESTRSGRRMELSMGPIQANHT GTGLLLTLQPEQKFQKVKGFGGAMT DAAALNILALSPPAQNLLLKSYFSE EGIGYNIIRVPMASCDFSIRTYTYA DTPDDFQLHNFSLPEEDTKLKIPLI HRALQLAQRPVSLLASPWTSPTWLK TNGAVNGKGSLKGQPGDIYHQTWAR YFVKFLDAYAEHKLQFWAVTAENEP SAGLLSGYPFQCLGFTPEHQRDFIA RDLGPTLANSTHHNVRLLMLDDQRL LLPHWAKVVLTDPEAAKYVHGIAVH WYLDFLAPAKATLGETHRLFPNTML FASEACVGSKFWEQSVRLGSWDRGM QYSHSIITNLLYHVVGWTDWNLALN PEGGPNWVRNFVDSPIIVDITKDTF YKQPMFYHLGHFSKFIPEGSQRVGL VASQKNDLDAVALMHPDGSAVVVVL NRSSKDVPLTIKDPAVGFLETISPG YSIHTYLWRRQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GBA glucosidase, beta, acid [ Homo sapiens ]
• Official Symbol: GBA
• Synonyms: GBA; glucosidase, beta, acid; GLUC, glucosidase, beta; acid (includes glucosylceramidase), glucosylceramidase; glucosylceramidase; GBA1; alglucerase; imiglucerase; acid beta-glucosidase; beta-glucocerebrosidase; lysosomal glucocerebrosidase; D-glucosyl-N-acylsphingosine glucohydrolase; GCB; GLUC
• Gene ID: 2629
• mRNA Refseq: NM_000157
• Protein Refseq: NP_000148
• MIM: 606463
• UniProt ID: P04062

Reviews

06/08/2022

This guidance allows me to design and implement experiments effectively while adhering to best practices, enhancing the reliability and reproducibility of my results.

08/08/2021

They ensure the purity, integrity, and functionality of GBA protein through rigorous quality control measures.

05/02/2018

The manufacturer's commitment to quality control is essential in achieving reliable and consistent outcomes