Recombinant Full Length Human GLE1 Protein, GST-tagged
Cat.No. : | GLE1-5327HF |
Product Overview : | Human GLE1 full-length ORF ( AAH30012.1, 1 a.a. - 698 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 106.3 kDa |
Protein Length : | 698 amino acids |
AA Sequence : | MPSEGRCWETLKALRSSDKGRLCYY RDWLLRREDVLEECMSLPKLSSYSG WVVEHVLPHMQENQPLSETSPSSTS ASALDQPSFVPKSPDASSAFSPASP ATPNGTKGKDESQHTESMVLQSSRG IKVEDCVRMYELVHRMKGTEGLRLW QEEQERKVQALSEMASEQLKRFDEW KELKQHKEFQDLREVMEKSSREALG HQEKLKAEHRHRAKILNLKLREAEQ QRVKQAEQERLRKEEGQIRLRALYA LQEEMLQLSQQLDASEQHKALLKVD LAAFQTRGNQLCSLISGIIRASSES SYPTAESQAEAERALREMRDLLMNL GQEITRACEDKRRQDEEEAQVKLQE AQMQQGPEAHKEPPAPSQGPGGKQN EDLQVKVQDITMQWYQQLQDASMQC VLTFEGLTNSKDSQAKKIKMDLQKA ATIPVSQISTIAGSKLKEIFDKIHS LLSGKPVQSGGRSVSVTLNPQGLDF VQYKLAEKFVKQGEEEVASHHEAAF PIAVVASGIWELHPRVGDLILAHLH KKCPYSVPFYPTFKEGMALEDYQRM LGYQVKDSKVEQQDNFLKRMSGMIR LYAAIIQLRWPYGNQQEIHPHGLNH GWRWLAQILNMEPLSDVTATLLFDF LEVCGNALMKQYQVQFWKMLILIKE DYFPRIEAITSSGQMGSFIRLKQFL EKCLQHKDIPVPKGFLTSSFWRS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GLE1 GLE1 RNA export mediator homolog (yeast) [ Homo sapiens ] |
Official Symbol : | GLE1 |
Synonyms : | GLE1; GLE1 RNA export mediator homolog (yeast); GLE1 (yeast homolog) like, RNA export mediator, GLE1 RNA export mediator (yeast), GLE1 RNA export mediator like (yeast), GLE1L, LCCS1, lethal congenital contracture syndrome 1; nucleoporin GLE1; hGLE1; GLE1-like protein; GLE1-like, RNA export mediator; LCCS; GLE1L; LCCS1; |
Gene ID : | 2733 |
mRNA Refseq : | NM_001003722 |
Protein Refseq : | NP_001003722 |
MIM : | 603371 |
UniProt ID : | Q53GS7 |
Products Types
◆ Recombinant Protein | ||
GLE1-4952H | Recombinant Human GLE1 Protein, GST-tagged | +Inquiry |
GLE1-3593M | Recombinant Mouse GLE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gle1-3223M | Recombinant Mouse Gle1 Protein, Myc/DDK-tagged | +Inquiry |
GLE1-2217R | Recombinant Rat GLE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GLE1-1686R | Recombinant Rhesus Macaque GLE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GLE1-5906HCL | Recombinant Human GLE1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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