Recombinant Full Length Human GP1BA Protein, GST-tagged
Cat.No. : | GP1BA-5462HF |
Product Overview : | Human GP1BA full-length ORF ( AAH27955.1, 1 a.a. - 626 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 95.4 kDa |
Protein Length : | 626 amino acids |
AA Sequence : | MPLLLLLLLLPSPLHPHPICEVSKV ASHLEVNCDKRNLTALPPDLPKDTT ILHLSENLLYTFSLATLMPYTRLTQ LNLDRCELTKLQVDGTLPVLGTLDL SHNQLQSLPLLGQTLPALTVLDVSF NRLTSLPLGALRGLGELQELYLKGN ELKTLPPGLLTPTPKLEKLSLANNN LTELPAGLLNGLENLDTLLLQENSL YTIPKGFFGSHLLPFAFLHGNPWLC NCEILYFRRWLQDNAENVYVWKQGV DVKAMTSNVASVQCDNSDKFPVYKY PGKGCPTLGDEGDTDLYDYYPEEDT EGDKVRATRTVVKFPTKAHTTPWGL FYSWSTASLDSQMPSSLHPTQESTK EQTTFPPRWTPNFTLHMESITFSKT PKSTTEPTPSPTTSEPVPEPAPNMT TLEPTPSPTTPEPTSEPAPSPTTPE PTPIPTIATSPTILVSATSLITPKS TFLTTTKPVSLLESTKKTIPELDQP PKLRGVLQGHLESSRNDPFLHPDFC CLLPLGFYVLGLFWLLFASVVLILL LSWVGHVKPQALDSGQGAALTTATQ TTHLELQRGRQVTVPRAWLLFLRGS LPTFRSSLFLWVRPNGRLGPLVAGR RPSALSQGRGQDLLSTVSIRYSGHS L |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GP1BA glycoprotein Ib (platelet), alpha polypeptide [ Homo sapiens ] |
Official Symbol : | GP1BA |
Synonyms : | GP1BA; glycoprotein Ib (platelet), alpha polypeptide; GP1B; platelet glycoprotein Ib alpha chain; CD42b; GP-Ib alpha; antigen CD42b-alpha; platelet membrane glycoprotein 1b-alpha subunit; BSS; VWDP; CD42B; GPIbA; BDPLT1; BDPLT3; DBPLT3; CD42b-alpha; MGC34595; |
Gene ID : | 2811 |
mRNA Refseq : | NM_000173 |
Protein Refseq : | NP_000164 |
MIM : | 606672 |
UniProt ID : | P07359 |
Products Types
◆ Recombinant Protein | ||
GP1BA-1401H | Recombinant Human GP1BA Protein (17-531 aa), His-tagged | +Inquiry |
GP1BA-531H | Recombinant Human GP1BA Protein (17-505 aa), His-tagged | +Inquiry |
GP1BA-683H | Recombinant Human GP1BA Protein, His-tagged | +Inquiry |
GP1BA-2584H | Recombinant Human GP1BA protein(381-450 aa), N-SUMO & C-His-tagged | +Inquiry |
GP1BA-16H | Recombinant Human GP1BA Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GP1BA-5823HCL | Recombinant Human GP1BA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket