| Description : |
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
112.090kDa inclusive of tags |
| Protein Length : |
782 amino acids |
| AA Sequence : |
MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAP QGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVP VPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNEC SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRA TEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENP FAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMD DDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNY RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAP ASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPS AAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFV IEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEK TEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF LGWDDDYWSVDPLDRAMAELAA |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
