Recombinant Full Length Human GUSB Protein, GST-tagged

• Cat.No.: GUSB-3357HF
• Product Overview: Human GUSB full-length ORF ( AAH14142.1, 22 a.a. - 651 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]). The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).[supplied by OMIM
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 94.82 kDa
• Protein Length: 651 amino acids
• AA Sequence: GLQGGMLYPQESPSRECKELDGLWS FRADFSDNRRRGFEEQWYRRPLWES GPTVDMPVPSSFNDISQDWRLRHFV GWVWYEREVILPERWTQDLRTRVVL RIGSAHSYAIVWVNGVDTLEHEGGY LPFEADISNLVQVGPLPSRLRITIA INNTLTPTTLPPGTIQYLTDTSKYP KGYFVQNTYFDFFNYAGLQRSVLLY TTPTTYIDDITVTTSVEQDSGLVNY QISVKGSNLFKLEVRLLDAENKVVA NGTGTQGQLKVPGVSLWWPYLMHER PAYLYSLEVQLTAQTSLGPVSDFYT LPVGIRTVAVTKSQFLINGKPFYFH GVNKHEDADIRGKGFDWPLLVKDFN LLRWLGANAFRTSHYPYAEEVMQMC DRYGIVVIDECPGVGLALPQFFNNV SLHHHMQVMEEVVRRDKNHPAVVMW SVANEPASHLESAGYYLKMVIAHTK SLDPSRPVTFVSNSNYAADKGAPYV DVICLNSYYSWYHDYGHLELIQLQL ATQFENWYKKYQKPIIQSEYGAETI AGFHQDPPLMFTEEYQKSLLEQYHL GLDQKRRKYVVGELIWNFADFMTEQ SPTRVLGNKKGIFTRQRQPKSAAFL LRERYWKIANETRYPHSVAKSQCLE NSLFT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GUSB glucuronidase, beta [ Homo sapiens ]
• Official Symbol: GUSB
• Synonyms: GUSB; glucuronidase, beta; beta-glucuronidase; beta-G1; beta-D-glucuronidase; BG; MPS7; FLJ39445
• Gene ID: 2990
• mRNA Refseq: NM_000181
• Protein Refseq: NP_000172
• MIM: 611499
• UniProt ID: P08236