Recombinant Full Length Human HNF4A Protein, GST-tagged
Cat.No. : | HNF4A-3676HF |
Product Overview : | Human HNF4A full-length ORF ( NP_849180.1, 1 a.a. - 464 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 78 kDa |
Protein Length : | 464 amino acids |
AA Sequence : | MRLSKTLVDMDMADYSAALDPAYTT LEFENVQVLTMGNDTSPSEGTNLNA PNSLGVSALCAICGDRATGKHYGAS SCDGCKGFFRRSVRKNHMYSCRFSR QCVVDKDKRNQCRYCRLKKCFRAGM KKEAVQNERDRISTRRSSYEDSSLP SINALLQAEVLSRQITSPVSGINGD IRAKKIASIADVCESMKEQLLVLVE WAKYIPAFCELPLDDQVALLRAHAG EHLLLGATKRSMVFKDVLLLGNDYI VPRHCPELAEMSRVSIRILDELVLP FQELQIDDNEYAYLKAIIFFDPDAK GLSDPGKIKRLRSQVQVSLEDYIND RQYDSRGRFGELLLLLPTLQSITWQ MIEQIQFIKLFGMAKIDNLLQEMLL GGSPSDAPHAHHPLHPHLMQEHMGT NVIVANTMPTHLSNGQMSTPETPQP SPPGGSGSEPYKLLPGAVATIVKPL SAIPQPTITKQEVI |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HNF4A hepatocyte nuclear factor 4, alpha [ Homo sapiens ] |
Official Symbol : | HNF4A |
Synonyms : | HNF4A; hepatocyte nuclear factor 4, alpha; MODY, MODY1, TCF14; hepatocyte nuclear factor 4-alpha; HNF4; NR2A1; TCF-14; HNF-4-alpha; HNF4alpha10/11/12; transcription factor 14; transcription factor-14; transcription factor HNF-4; hepatic nuclear factor 4 alpha; nuclear receptor subfamily 2 group A member 1; TCF; MODY; MODY1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha; FLJ39654; |
Gene ID : | 3172 |
mRNA Refseq : | NM_000457 |
Protein Refseq : | NP_000448 |
MIM : | 600281 |
UniProt ID : | P41235 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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