Recombinant Full Length Human HTRA1 Protein, GST-tagged

Species :	Human
Source :	In Vitro Cell Free System
Tag :	GST
Protein Length :	447 amino acids
Description :	This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq
Molecular Mass :	74.9 kDa
AA Sequence :	MGWAARPRALAPAAPEALLHSPRRRSPALALSNTYANLCQQRAGVRLLRGVRRARGRRVRPAGGPVRRGAAVRGALRGASLGHGAAARAGRPLCVRQQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRGGNEDIMITVIPEEIDP
Applications :	Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array
Notes :	Best use within three months from the date of receipt of this protein.
Storage :	Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer :	50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Name	HTRA1 HtrA serine peptidase 1 [ Homo sapiens ]
Official Symbol	HTRA1
Synonyms	HTRA1; HtrA serine peptidase 1; protease, serine, 11 (IGF binding) , PRSS11; serine protease HTRA1; HtrA; IGFBP5 protease; IGFBP5-protease; protease, serine, 11 (IGF binding); high-temperature requirement A serine peptidase 1; L56; ARMD7; ORF480; PRSS11;
Gene ID	5654
mRNA Refseq	NM_002775
Protein Refseq	NP_002766
MIM	602194
UniProt ID	Q92743