Recombinant Full-length Human IGL Protein, GST tagged

• Cat.No.: IGL-19HFL
• Product Overview: Human IGL full-length ORF ( AAH89414.1, 1 a.a. - 232 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat germ cell free in vitro.

Specification

• Species: Human
• Source: Wheat germ cell free in vitro
• Tag: GST
• Protein Length: 1-232 aa
• Description: Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species.
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Molecular Mass: 51.2 kDa
• AASequence: MAWTPLLLPLLTFCTVSEASYDLTQPPSVSVSPGQTARITCSGDALPRKYAFWYQQKSGQAPVLVIYEDSKRPSGIPERFSGSSSGTMATLTISGAQVEDEGDYYCYSTDISGYPVFGGGTKVTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWRSHKSYSCQVTHEGSTVEKTVAPTECS
• Applications: Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Quality Control Testing: 12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Information

• Gene Name: IGL immunoglobulin lambda locus [ Homo sapiens (human) ]
• Official Symbol: IGL
• Synonyms: IGL; immunoglobulin lambda locus; IGL@; IGLC6; ig lambda-6 chain C region; immunoglobulin lambda gene cluster
• Gene ID: 3535