Recombinant Full Length Human KCNJ5 Protein, Flag tagged

• Cat.No.: KCNJ5-12HFL
• Product Overview: Recombinant protein of human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5) with C-terminal flag tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 1-419aa
• Description: This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas.
• Tag: C-Flag
• Molecular Mass: 47.5 kDa
• AA Sequence: MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSVTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Storage Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Concentration: >0.05 μg/μL as determined by microplate BCA method

Gene Information

• Gene Name: KCNJ5 potassium inwardly rectifying channel subfamily J member 5 [ Homo sapiens (human) ]
• Official Symbol: KCNJ5
• Synonyms: KCNJ5; potassium inwardly-rectifying channel, subfamily J, member 5; G protein-activated inward rectifier potassium channel 4; CIR; GIRK4; KATP1; Kir3.4; IRK-4; heart KATP channel; inward rectifier K+ channel KIR3.4; cardiac ATP-sensitive potassium channel; LQT13; KIR3.4
• Gene ID: 3762
• mRNA Refseq: NM_000890
• Protein Refseq: NP_000881
• MIM: 600734
• UniProt ID: P48544