Recombinant Full Length Human KIF20A Protein, C-Flag-tagged

• Cat.No.: KIF20A-1366HFL
• Product Overview: Recombinant Full Length Human KIF20A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including cleavage furrow; intercellular bridge; and midbody. Implicated in restrictive cardiomyopathy.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 100.1 kDa
• AA Sequence: MSQGILSPPAGLLSDDDVVVSPMFE STAADLGSVVRKNLLSDCSVVSTSL EDKQQVPSEDSMEKVKVYLR VRPLLPSELERQEDQGCVRIENVET LVLQAPKDSFALKSNERGIGQATHR FTFSQIFGPEVGQASFFNLT VKEMVKDVLKGQNWLIYTYGVTNSG KTHTIQGTIKDGGILPRSLALIFNS LQGQLHPTPDLKPLLSNEVI WLDSKQIRQEEMKKLSLLNGGLQEE ELSTSLKRSVYIESRIGTSTSFDSG IAGLSSISQCTSSSQLDETS HRWAQPDTAPLPVPANIRFSIWISF FEIYNELLYDLLEPPSQQRKRQTLR LCEDQNGNPYVKDLNWIHVQ DAEEAWKLLKVGRKNQSFASTHLNQ NSSRSHSIFSIRILHLQGEGDIVPK ISELSLCDLAGSERCKDQKS GERLKEAGNINTSLHTLGRCIAALR QNQQNRSKQNLVPFRDSKLTRVFQG FFTGRGRSCMIVNVNPCAST YDETLHVAKFSAIASQLVHAPPMQL GFPSLHSFIKEHSLQVSPSLEKGAK ADTGLDDDIENEADISMYGK EELLQVVEAMKTLLLKERQEKLQLE MHLRDEICNEMVEQMQQREQWCSEH LDTQKELLEEMYEEKLNILK ESLTSFYQEEIQERDEKIEELEALL QEARQQSVAHQQSGSELALRRSQRL AASASTQQLQEVKAKLQQCK AELNSTTEELHKYQKMLEPPPSAKP FTIDVDKKLEEGQKNIRLLRTELQK LGESLQSAERACCHSTGAGK LRQALTTCDDILIKQDQTLAELQNN MVLVKLDLRKKAACIAEQYHTVLKL QGQVSAKKRLGTNQENQQPN
  QQPPGKKPFLRNLLPRTPTCQSSTD CSPYARILRSRRSPLLKSGPFGKKY TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: KIF20A kinesin family member 20A [ Homo sapiens (human) ]
• Official Symbol: KIF20A
• Synonyms: RCM6; MKLP2; RAB6KIFL
• Gene ID: 10112
• mRNA Refseq: NM_005733.3
• Protein Refseq: NP_005724.1
• MIM: 605664
• UniProt ID: O95235