| Description : |
Enables eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Involved in several processes, including TORC1 signaling; cellular response to rapamycin; and posttranscriptional regulation of gene expression. Located in cytoplasmic stress granule. Colocalizes with TORC1 complex and polysomal ribosome. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
142.9 kDa |
| Protein Length : |
1096 amino acids |
| AA Sequence : |
MLWRVLLSKRPPFPHPELDFQEAPI PSCPGRLPGRKNSVALAAAPRKEPT GDREKPLPFPVLAPFSNPEHSAPAK VVRAAVPKQRKGSKVGDFGDAINWP TPGEIAHKSVQPQSHKPQPTRKLPP KKDMKEQEKGEGSDSKESPKTKSDE SGEEKNGDEDCQRGGQKKKGNKHKW VPLQIDMKPEVPREKLASRPTRPPE PRHIPANRGEIKGSESATYVPVAPP TPAWQPEIKPEPAWHDQDETSSVKS DGAGGARASFRGRGRGRGRGRGRGR GGTRTHFDYQFGYRKFDGVEGPRTP KYMNNITYYFDNVSSTELYSVDQEL LKDYIKRQIEYYFSVDNLERDFFLR RKMDADGFLPITLIASFHRVQALTT DISLIFAALKDSKVVEIVDEKVRRR EEPEKWPLPPIVDYSQTDFSQLLNC PEFVPRQHYQKETESAPGSPRAVTP VPTKTEEVSNLKTLPKGLSASLPDL DSENWIEVKKRPRPSPARPKKSEES RFSHLTSLPQQLPSQQLMSKDQDEQ EELDFLFDEEMEQMDGRKNTFTAWS DEESDYEIDDRDVNKILIVTQTPHY MRRHPGGDRTGNHTSRAKMSAELAK VINDGLFYYEQDLWAEKFEPEYSQI KQEVENFKKVNMISREQFDTLTPEP PVDPNQEVPPGPPRFQQVPTDALAN KLFGAPEPSTIARSLPTTVPESPNY RNTRTPRTPRTPQLKDSSQTSRFYP VVKEGRTLDAKMPRKRKTRHSSNPP LESHVGWVMDSREHRPRTASISSSP SEGTPTVGSYGCTPQSLPKFQHPSH ELLKENGFTQHVYHKYRRRCLNERK RLGIGQSQEMNTLFRFWSFFLRDHF NKKMYEEFKQLALEDAKEGYRYGLE CLFRYYSYGLEKKFRLDIFKDFQEE TVKDYEAGQLYGLEKFWAFLKYSKA KNLDIDPKLQEYLGKFRRLEDFRVD PPMGEEGNHKRHSVVAGGGGGEGRK RCPSQSSSRPAAMISQPPTPPTGQP VREDAKWTSQHSNTQTLGK |
| Applications : |
ELISA; WB-Re; AP; Array |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
