Recombinant Full Length Human menin 1 Protein, His&Avi tagged

• Cat.No.: MEN1-02H
• Product Overview: Recombinant full length human menin 1 Protein with His&Avi tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: 1-610aa
• Description: This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones
• Tag: His&Avi
• Molecular Mass: 71 kDa
• AA Sequence: MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPVGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQSQGTQSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREAEAAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVAGTARGPEGGSTAQVPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGLHHHHHHHHHHGLNDIFEAQKIEWHE
• Endotoxin: < 0.1 EU/μg by LAL
• Purity: > 85% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile 25mM Hepes, 150mM NaCl, pH 8.0, 2mM DTT
• Concentration: 0.024 mg/mL by Bradford

Gene Information

• Gene Name: MEN1 menin 1 [ Homo sapiens (human) ]
• Official Symbol: MEN1
• Synonyms: MEN1; multiple endocrine neoplasia I; menin; endocrine adenomatosis, multiple; MEAI; SCG2; MENIN
• Gene ID: 4221
• mRNA Refseq: NM_000244
• Protein Refseq: NP_000235
• MIM: 613733
• UniProt ID: O00255