Recombinant Full Length Human MKRN3 Protein, GST-tagged

• Cat.No.: MKRN3-6346HF
• Product Overview: Human MKRN3 full-length ORF (AAH44639.1, 1 a.a. - 507 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 82.17 kDa
• Protein Length: 507 amino acids
• AA Sequence: MEEPAAPSEAHEAAGAQAGAEAARE GVSGPDLPVCEPSGESAAPDSALPH AARGWAPFPVAPVPAHLRRGGLRPA PASGGGAWPSPLPSRSSGIWTKQII CRYYIHGQCKEGENCRYSHDLSGRK MATEGGVSPPGASAGGGPSTAAHIE PPTQEVAEAPPAASSLSLPVIGSAA ERGFFEAERDNADRGAAGGAGVESW ADAIEFVPGQPYRGRWVASAPEAPL QSSETERKQMAVGSGLRFCYYASRG VCFRGESCMYLHGDICDMCGLQTLH PMDAAQREEHMRACIEAHEKDMELS FAVQRGMDKVCGICMEVVYEKANPN DRRFGILSNCNHSFCIRCIRRWRSA RQFENRIVKSCPQCRVTSELVIPSE FWVEEEEEKQKLIQQYKEAMSNKAC RYFAEGRGNCPFGDTCFYKHEYPEG WGDEPPGPGGGSFSAYWHQLVEPVR MGEGNMLYKSIKKELVVLRLASLLF KRFLSLRDELPFSEDQWDLLHYELE EYFNLIL
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MKRN3 makorin ring finger protein 3 [ Homo sapiens ]
• Official Symbol: MKRN3
• Synonyms: MKRN3; makorin ring finger protein 3; D15S9, ZNF127; probable E3 ubiquitin-protein ligase makorin-3; MGC88288; RNF63; ZFP127; zinc finger protein 127; RING finger protein 63; D15S9; ZNF127
• Gene ID: 7681
• mRNA Refseq: NM_005664
• Protein Refseq: NP_005655
• MIM: 603856
• UniProt ID: Q13064