Recombinant Full Length Human NCKIPSD Protein, C-Flag-tagged

• Cat.No.: NCKIPSD-2182HFL
• Product Overview: Recombinant Full Length Human NCKIPSD Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: Q9NZQ3
• AA Sequence: MYRALYAFRSAEPNALAFAAGETFL VLERSSAHWWLAARARSGETGYVPP AYLRRLQGLEQDVLQAIDRA IEAVHNTAMRDGGKYSLEQRGVLQK LIHHRKETLSRRGPSASSVAVMTSS TSDHHLDAAAARQPNGVCRA GFERQHSLPSSEHLGADGGLYQIPP QPRRAAPTTPPPPVKRRDREALMAS GSGGHNTMPSGGNSVSSGSS VSSTSLDTLYTSSSPSEPGSSCSPT PPPVPRRGTHTTVSQVQPPPSKASA PEPPAEEEVATGTTSASDDL EALGTLSLGTTEEKAAAEAAVPRTI GAELMELVRRNTGLSHELCRVAIGI IVGHIQASVPASSPVMEQVL LSLVEGKDLSMALPSGQVCHDQQRL EVIFADLARRKDDAQQRSWALYEDE GVIRCYLEELLHILTDADPE VCKKMCKRNEFESVLALVAYYQMEH RASLRLLLLKCFGAMCSLDAAIIST LVSSVLPVELARDMQTDTQD HQKLCYSALILAMVFSMGEAVPYAH YEHLGTPFAQFLLNIVEDGLPLDTT EQLPDLCVNLLLALNLHLPA ADQNVIMAALSKHANVKIFSEKLLL LLNRGDDPVRIFKHEPQPPHSVLKF LQDVFGSPATAAIFYHTDMM ALIDITVRHIADLSPGDKLRMESLS LMHAIVRTTPYLQHRHRLPDLQAIL RRILNEEETSPQCQMDRMIV REMCKEFLVLGEAPS SGPTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: NCKIPSD NCK interacting protein with SH3 domain [ Homo sapiens (human) ]
• Official Symbol: NCKIPSD
• Synonyms: DIP; DIP1; ORF1; WISH; VIP54; AF3P21; SPIN90; WASLBP
• Gene ID: 51517
• mRNA Refseq: NM_184231.3
• Protein Refseq: NP_909119.1
• MIM: 606671
• UniProt ID: Q9NZQ3