Recombinant Full Length Human NOVA1 Protein, GST-tagged

• Cat.No.: NOVA1-6720HF
• Product Overview: Human NOVA1 full-length ORF ( NP_002506.2, 1 a.a. - 507 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 81.29 kDa
• Protein Length: 507 amino acids
• AA Sequence: MMAAAPIQQNGTHTGVPIDLDPPDS RKRPLEAPPEAGSTKRTNTGEDGQY FLKVLIPSYAAGSIIGKGGQTIVQL QKETGATIKLSKSKDFYPGTTERVC LIQGTVEALNAVHGFIAEKIREMPQ NVAKTEPVSILQPQTTVNPDRIKQT LPSSPTTTKSSPSDPMTTSRANQVK IIVPNSTAGLIIGKGGATVKAVMEQ SGAWVQLSQKPDGINLQERVVTVSG EPEQNRKAVELIIQKIQEDPQSGSC LNISYANVTGPVANSNPTGSPYANT AEVLPTAAAAAGLLGHANLAGVAAF PAVLSGFTGNDLVAITSALNTLASY GYNLNTLGLGLSQAAATGALAAAAA SANPAAAAANLLATYASEASASGST AGGTAGTFALGSLAAATAATNGYFG AASPLAASAILGTEKSTDGSKDVVE IAVPENLVGAILGKGGKTLVEYQEL TGARIQISKKGEFVPGTRNRKVTIT GTPAATQAAQYLITQRITYEQGVRA ANPQKVG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NOVA1 neuro-oncological ventral antigen 1 [ Homo sapiens ]
• Official Symbol: NOVA1
• Synonyms: NOVA1; neuro-oncological ventral antigen 1; RNA-binding protein Nova-1; paraneoplastic Ri antigen; onconeural ventral antigen 1; ventral neuron-specific protein 1; Nova-1
• Gene ID: 4857
• mRNA Refseq: NM_002515
• Protein Refseq: NP_002506
• MIM: 602157
• UniProt ID: P51513