Recombinant Full Length Human NR3C1 Protein, GST-tagged
Cat.No. : | NR3C1-6743HF |
Product Overview : | Human NR3C1 full-length ORF ( NP_000167.1, 1 a.a. - 777 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 112.1 kDa |
Protein Length : | 777 amino acids |
AA Sequence : | MDSKESLTPGREENPSSVLAQERGD VMDFYKTLRGGATVKVSASSPSLAV ASQSDSKQRRLLVDFPKGSVSNAQQ PDLSKAVSLSMGLYMGETETKVMGN DLGFPQQGQISLSSGETDLKLLEES IANLNRSTSVPENPKSSASTAVSAA PTEKEFPKTHSDVSSEQQHLKGQTG TNGGNVKLYTTDQSTFDILQDLEFS SGSPGKETNESPWRSDLLIDENCLL SPLAGEDDSFLLEGNSNEDCKPLIL PDTKPKIKDNGDLVLSSPSNVTLPQ VKTEKEDFIELCTPGVIKQEKLGTV YCQASFPGANIIGNKMSAISVHGVS TSGGQMYHYDMNTASLSQQQDQKPI FNVIPPIPVGSENWNRCQGSGDDNL TSLGTLNFPGRTVFSNGYSSPSMRP DVSSPPSSSSTATTGPPPKLCLVCS DEASGCHYGVLTCGSCKVFFKRAVE GQHNYLCAGRNDCIIDKIRRKNCPA CRYRKCLQAGMNLEARKTKKKIKGI QQATTGVSQETSENPGNKTIVPATL PQLTPTLVSLLEVIEPEVLYAGYDS SVPDSTWRIMTTLNMLGGRQVIAAV KWAKAIPGFRNLHLDDQMTLLQYSW MFLMAFALGWRSYRQSSANLLCFAP DLIINEQRMTLPCMYDQCKHMLYVS SELHRLQVSYEEYLCMKTLLLLSSV PKDGLKSQELFDEIRMTYIKELGKA IVKREGNSSQNWQRFYQLTKLLDSM HEVVENLLNYCFQTFLDKTMSIEFP EMLAEIITNQIPKYSNGNIKKLLFH QK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) [ Homo sapiens ] |
Official Symbol : | NR3C1 |
Synonyms : | NR3C1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); GRL, nuclear receptor subfamily 3, group C, member 1; glucocorticoid receptor; GR; glucocorticoid nuclear receptor variant 1; GCR; GRL; GCCR; |
Gene ID : | 2908 |
mRNA Refseq : | NM_000176 |
Protein Refseq : | NP_000167 |
MIM : | 138040 |
UniProt ID : | P04150 |
Products Types
◆ Recombinant Protein | ||
NR3C1-2507H | Recombinant Human NR3C1 Protein, His-tagged | +Inquiry |
NR3C1-1853H | Recombinant Human NR3C1 Protein, His&GST-tagged | +Inquiry |
Nr3c1-1854M | Recombinant Mouse Nr3c1 Protein, His-tagged | +Inquiry |
NR3C1-6090H | Recombinant Human NR3C1 Protein, GST-tagged | +Inquiry |
NR3C1-2750H | Recombinant Human NR3C1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NR3C1-1218HCL | Recombinant Human NR3C1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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