Recombinant Full Length Human PMAIP1 Protein, C-Flag-tagged

• Cat.No.: PMAIP1-686HFL
• Product Overview: Recombinant Full Length Human PMAIP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene belongs to a pro-apoptotic subfamily within the BCL-2 protein family, referred to as the BCL-2 homology domain 3 (BH3)-only subfamily, which determine whether a cell commits to apoptosis. In response to death-inducing stimuli, BH3-only members inhibit the anti-apoptotic BCL-2 family members, which under steady-state conditions keep the multi-BH domain proteins BAX and BAK, in an inactive state.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 5.8 kDa
• AA Sequence: MPGKKARKNAQPSPARAPAELEVEC ATQLRRFGDKLNFRQKLLNLISKLF CSGTTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: p53 signaling pathway

Gene Information

• Gene Name: PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 [ Homo sapiens (human) ]
• Official Symbol: PMAIP1
• Synonyms: APR; NOXA
• Gene ID: 5366
• mRNA Refseq: NM_021127.3
• Protein Refseq: NP_066950.1
• MIM: 604959
• UniProt ID: Q13794