Recombinant Full Length Human PMP22 Protein

• Cat.No.: PMP22-374HF
• Product Overview: Recombinant full length Human PMP22 with proprietary tag; Predicted MWt 44.9 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 160 amino acids
• Description: This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein.
• Form: Liquid
• Molecular Mass: 44.900kDa inclusive of tags
• AA Sequence: MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: PMP22 peripheral myelin protein 22 [ Homo sapiens ]
• Official Symbol: PMP22
• Synonyms: PMP22; peripheral myelin protein 22; GAS 3; HNPP; Sp110
• Gene ID: 5376
• mRNA Refseq: NM_000304
• Protein Refseq: NP_000295
• MIM: 601097
• UniProt ID: Q01453