Recombinant Full Length Human PNPLA6 Protein, C-Flag-tagged
Cat.No. : | PNPLA6-920HFL |
Product Overview : | Recombinant Full Length Human PNPLA6 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 150.8 kDa |
AA Sequence : | MEAPLQTGMMGTSSHGLATNSSGAK VAERDGFQDVLAPGEGSAGRICGAQ PVPFVPQVLGVMIGAGVAVV VTAVLILLVVRRLRVPKTPAPDGPR YRFRKRDKVLFYGRKIMRKVSQSTS SLVDTSVSATSRPRMRKKLK MLNIAKKILRIQKETPTLQRKEPPP AVLEADLTEGDLANSHLPSEVLYML KNVRVLGHFEKPLFLELCRH MVFQRLGQGDYVFRPGQPDASIYVV QDGLLELCLPGPDGKECVVKEVVPG DSVNSLLSILDVITGHQHPQ RTVSARAARDSTVLRLPVEAFSAVF TKYPESLVRVVQIIMVRLQRVTFLA LHNYLGLTNELFSHEIQPLR LFPSPGLPTRTSPVRGSKRMVSTSA TDEPRETPGRPPDPTGAPLPGPTGD PVKPTSLETPSAPLLSRCVS MPGDISGLQGGPRSDFDMAYERGRI SVSLQEEASGGSLAAPARTPTQEPR EQPAGACEYSYCEDESATGG CPFGPYQGRQTSSIFEAAKQELAKL MRIEDPSLLNSRVLLHHAKAGTIIA RQGDQDVSLHFVLWGCLHVY QRMIDKAEDVCLFVAQPGELVGQLA VLTGEPLIFTLRAQRDCTFLRISKS DFYEIMRAQPSVVLSAAHTV AARMSPFVRQMDFAIDWTAVEAGRA LYRQGDRSDCTYIVLNGRLRSVIQR GSGKKELVGEYGRGDLIGVV EALTRQPRATTVHAVRDTELAKLPE GTLGHIKRRYPQVVTRLIHLLSQKI LGNLQQLQGPFPAGSGLGVP PHSELTNPASNLATVAILPVCAEVP MVAFTLELQHALQAIGPTLLLNSDI IRARLGASALDSIQEFRLSG WLAQQEDAHRIVLYQTDASLTPWTV RCLRQADCILIVGLGDQEPTLGQLE QMLENTAVRALKQLVLLHRE EGAGPTRTVEWLNMRSWCSGHLHLR CPRRLFSRRSPAKLHELYEKVFSRR ADRHSDFSRLARVLTGNTIA LVLGGGGARGCSHIGVLKALEEAGV PVDLVGGTSIGSFIGALYAEERSAS RTKQRAREWAKSMTSVLEPV LDLTYPVTSMFTGSAFNRSIHRVFQ DKQIEDLWLPYFNVTTDITASAMRV HKDGSLWRYVRASMTLSGYL PPLCDPKDGHLLMDGGYINNLPADI ARSMGAKTVIAIDVGSQDETDLSTY GDSLSGWWLLWKRLNPWADK VKVPDMAEIQSRLAYVSCVRQLEVV KSSSYCEYLRPPIDCFKTMDFGKFD QIYDVGYQYGKAVFGGWSRG NVIEKMLTDRRSTDLNESRRADVLA FPSSGFTDLAEIVSRIEPPTSYVSD GCADGEESDCLTEYEEDAGP DCSRDEGGSPEGASPSTASEMEEEK SILRQRRCLPQEPPGSATDATRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Transmembrane |
Gene Name : | PNPLA6 patatin like phospholipase domain containing 6 [ Homo sapiens (human) ] |
Official Symbol : | PNPLA6 |
Synonyms : | NTE; sws; BNHS; LNMS; OMCS; SPG39; NTEMND; iPLA2delta |
Gene ID : | 10908 |
mRNA Refseq : | NM_001166111.2 |
Protein Refseq : | NP_001159583.1 |
MIM : | 603197 |
UniProt ID : | Q8IY17 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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