Recombinant Full Length Human RAB3GAP1 Protein, C-Flag-tagged

• Cat.No.: RAB3GAP1-1954HFL
• Product Overview: Recombinant Full Length Human RAB3GAP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 111.7 kDa
• AA Sequence: MAADSEPESEVFEITDFTTASEWER FISKVEEVLNDWKLIGNSLGKPLEK GIFTSGTWEEKSDEISFADF KFSVTHHYLVQESTDKEGKDELLED VVPQSMQDLLGMNNDFPPRAHCLVR WYGLREFVVIAPAAHSDAVL SESKCNLLLSSVSIALGNTGCQVPL FVQIHHKWRRMYVGECQGPGVRTDF EMVHLRKVPNQYTHLSGLLD IFKSKIGCPLTPLPPVSIAIRFTYV LQDWQQYFWPQQPPDIDALVGGEVG GLEFGKLPFGACEDPISELH LATTWPHLTEGIIVDNDVYSDLDPI QAPHWSVRVRKAENPQCLLGDFVTE FFKICRRKESTDEILGRSAF EEEGKETADITHALSKLTEPASVPI HKLSVSNMVHTAKKKIRKHRGVEES PLNNDVLNTILLFLFPDAVS EKPLDGTTSTDNNNPPSESEDYNLY NQFKSAPSDSLTYKLALCLCMINFY HGGLKGVAHLWQEFVLEMRF RWENNFLIPGLASGPPDLRCCLLHQ KLQMLNCCIERKKARDEGKKTSASD VTNIYPGDAGKAGDQLVPDN LKETDKEKGEVGKSWDSWSDSEEEF FECLSDTEELKGNGQESGKKGGPKE MANLRPEGRLYQHGKLTLLH NGEPLYIPVTQEPAPMTEDLLEEQS EVLAKLGTSAEGAHLRARMQSACLL SDMESFKAANPGCSLEDFVR WYSPRDYIEEEVIDEKGNVVLKGEL SARMKIPSNMWVEAWETAKPIPARR QRRLFDDTREAEKVLHYLAI QKPADLARHLLPCVIHAAVLKVKEE ESLENISSVKKIIKQIISHSSKVLH FPNPEDKKLEEIIHQITNVE ALIARARSLKAKFGTEKCEQEEEKE DLERFVSCLLEQPEVLVTGAGRGHA GRIIHKLFVNAQRLTESSDE AAAMTPPEEELKRMGSPEERRQNSV SDFPPPAGREFILRTTVPRPAPYSK ALPQRMYSVLTKEDFRLAGA FSSDTSFF TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: RAB3GAP1 RAB3 GTPase activating protein catalytic subunit 1 [ Homo sapiens (human) ]
• Official Symbol: RAB3GAP1
• Synonyms: P130; MARTS2; WARBM1; RAB3GAP; RAB3GAP130
• Gene ID: 22930
• mRNA Refseq: NM_001172435.2
• Protein Refseq: NP_001165906
• MIM: 602536
• UniProt ID: Q15042